Interactor 1: TP53B (P70399)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: Tp53bp1

Interactor 2: MDC1 (Q5PSV9)
Mediator of DNA damage checkpoint protein 1
Gene: MDC1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24324146
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT_2~BRCT_3
Common GO terms GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0035861 - site of double-strand break
GO:1990166 - protein localization to site of double-strand break
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1969
Mm

1 1707
+ Mm
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+ Dm
+ Dm
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+ Dm
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+ Dm
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+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025