HitPredict

Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 15456759, 34144977, 14576432, 17925232, 17500065
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT_2~BRCT_3
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045830 - positive regulation of isotype switching
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1972
Hs

1 1069
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Service provided by Combinatics, Japan

Last updated: 11Aug2025