Interactor 1: PARC (P72525)
DNA topoisomerase 4 subunit A (EC 5.6.2.2) (Topoisomerase IV subunit A)
Gene: PARC
Interactor 2: PARE (Q59961)
DNA topoisomerase 4 subunit B (EC 5.6.2.2) (Topoisomerase IV subunit B)
Gene: PARE
Species: Streptococcus pneumoniae TIGR4
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19448616 |
| Identification Methods | x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_gyraseB~DNA_topoisoIV, DNA_gyraseB_C~DNA_topoisoIV, DNA_topoisoIV~Toprim |
| Common GO terms | GO:0003677 - DNA binding GO:0005524 - ATP binding GO:0005694 - chromosome GO:0006265 - DNA topological change GO:0007059 - chromosome segregation and 1 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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| + | Ec | |
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| + | Sc | |
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| + | Mp |  |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
