Protein: IME2
Meiosis induction protein kinase IME2/SME1 (EC 2.7.11.1)

Gene: IME2
Organism: Saccharomyces cerevisiae S288C
Interactions: 125
UniProt ID: P32581

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

693083

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

2

17

Small-scale

0.789

High

693705

RIM4
Meiotic activator RIM4

2

8

Small-scale

0.778

High

627833

SIS1
Protein SIS1

1

9

High-throughput

0.691

High

693708

KOG1
Target of rapamycin complex 1 subunit KOG1

1

7

High-throughput

0.691

High

693707

NDT80
Meiosis-specific transcription factor NDT80

4

0

Small-scale

0.659

High

693686

IME2
Meiosis induction protein kinase IME2/SME1

1

18

Small-scale

0.647

High

693695

PP2C1
Protein phosphatase 2C homolog 1

1

12

High-throughput

0.647

High

693697

KKQ8
Probable serine/threonine-protein kinase KKQ8

1

19

High-throughput

0.647

High

693735

DMA2
E3 ubiquitin-protein ligase DMA2

1

1

High-throughput

0.647

High

693760

YP150
Putative serine/threonine-protein kinase YPL150W

1

13

High-throughput

0.647

High

633053

MAS5
Mitochondrial protein import protein MAS5

1

8

High-throughput

0.646

High

693696

MDJ1
DnaJ homolog 1, mitochondrial

1

9

High-throughput

0.646

High

693704

KSP1
Serine/threonine-protein kinase KSP1

1

20

High-throughput

0.646

High

500306

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

2

2

Small-scale

0.633

High

447787

CDC6
Cell division control protein 6

2

13

Small-scale

0.625

High

664403

HRR25
Casein kinase I homolog HRR25

1

11

Small-scale

0.618

High

693736

CRZ1
Transcriptional regulator CRZ1

1

0

High-throughput

0.614

High

693759

CMR3
Zinc finger protein CRM3

1

0

High-throughput

0.614

High

693703

SIC1
Protein SIC1

2

1

Small-scale

0.602

High

367871

EF1A
Elongation factor 1-alpha

2

6

High-throughput

0.602

High

693746

RRP5
rRNA biogenesis protein RRP5

1

2

High-throughput

0.579

High

692475

ZUO1
Zuotin

1

5

High-throughput

0.575

High

644742

RFA2
Replication factor A protein 2

2

6

Small-scale

0.550

High

597106

IME1
Meiosis-inducing protein 1

1

0

Small-scale

0.549

High

519913

TCPA
T-complex protein 1 subunit alpha

1

12

High-throughput

0.536

High

693709

TCPB
T-complex protein 1 subunit beta

1

15

High-throughput

0.536

High

693722

ASK10
Activator of SKN7 protein 10

1

3

High-throughput

0.536

High

693725

VID30
Vacuolar import and degradation protein 30

1

5

High-throughput

0.536

High

693728

CDH1
APC/C activator protein CDH1

1

18

High-throughput

0.536

High

693748

RGC1
Regulator of the glycerol channel 1

1

3

High-throughput

0.536

High

693755

ACM1
APC/C-CDH1 modulator 1

1

1

High-throughput

0.536

High

693741

MUB1
MYND-type zinc finger protein MUB1

1

0

High-throughput

0.513

High

356339

H4
Histone H4

1

5

Small-scale

0.501

High

389698

CDC25
Cell division control protein 25

1

2

High-throughput

0.501

High

549851

UBC5
Ubiquitin-conjugating enzyme E2-16 kDa

1

3

High-throughput

0.501

High

562203

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

7

High-throughput

0.501

High

622152

MCM3
DNA replication licensing factor MCM3

1

16

Small-scale

0.501

High

667556

MCM2
DNA replication licensing factor MCM2

1

14

Small-scale

0.501

High

667840

MCM5
Minichromosome maintenance protein 5

1

13

Small-scale

0.501

High

675513

MCM4
DNA replication licensing factor MCM4

1

14

Small-scale

0.501

High

685405

MLF3
Protein MLF3

1

2

High-throughput

0.501

High

685426

SYKM
Lysine--tRNA ligase, mitochondrial

1

1

High-throughput

0.501

High

693427

PAH1
Phosphatidic acid phosphohydrolase 1

1

2

High-throughput

0.501

High

693687

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

4

High-throughput

0.501

High

693689

KU70
ATP-dependent DNA helicase II subunit 1

1

5

High-throughput

0.501

High

693690

ORC2
Origin recognition complex subunit 2

1

6

Small-scale

0.501

High

693699

MCM7
DNA replication licensing factor MCM7

1

13

Small-scale

0.501

High

693706

ORC6
Origin recognition complex subunit 6

1

1

Small-scale

0.501

High

693712

VHS2
Protein VHS2

1

2

High-throughput

0.501

High

693713

SYA
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.501

High

693716

BUD27
Bud site selection protein 27

1

1

High-throughput

0.501

High

693717

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

5

High-throughput

0.501

High

693726

MCM6
DNA replication licensing factor MCM6

1

16

Small-scale

0.501

High

693730

YG3A
Uncharacterized protein YGR130C

1

15

High-throughput

0.501

High

693731

REXO1
RNA exonuclease 1

1

2

High-throughput

0.501

High

693732

H1
Histone H1

1

1

Small-scale

0.501

High

693734

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

9

High-throughput

0.501

High

693737

ORC1
Origin recognition complex subunit 1

1

18

Small-scale

0.501

High

693739

ORC4
Origin recognition complex subunit 4

1

13

Small-scale

0.501

High

693745

YM11A
Transposon Ty1-ML1 Gag polyprotein

1

4

High-throughput

0.501

High

693751

BDF2
Bromodomain-containing factor 2

1

12

High-throughput

0.501

High

693758

SAS10
Something about silencing protein 10

1

2

High-throughput

0.501

High

693764

YN11A
Transposon Ty1-NL1 Gag polyprotein

1

5

High-throughput

0.501

High

693765

YD21A
Transposon Ty2-DR1 Gag polyprotein

1

8

High-throughput

0.501

High

341969

ATPB
ATP synthase subunit beta, mitochondrial

1

15

High-throughput

0.500

High

360806

TBB
Tubulin beta chain

1

7

High-throughput

0.500

High

381439

GAL1
Galactokinase

1

2

High-throughput

0.500

High

423802

ATPA
ATP synthase subunit alpha, mitochondrial

1

15

High-throughput

0.500

High

454249

TBA1
Tubulin alpha-1 chain

1

8

High-throughput

0.500

High

454579

TBA3
Tubulin alpha-3 chain

1

10

High-throughput

0.500

High

498475

METK1
S-adenosylmethionine synthase 1

1

3

High-throughput

0.500

High

555911

VATB
V-type proton ATPase subunit B

1

15

High-throughput

0.500

High

588002

HSP60
Heat shock protein 60, mitochondrial

1

13

High-throughput

0.500

High

693720

TCPQ
T-complex protein 1 subunit theta

1

13

High-throughput

0.500

High

693753

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

693761

HSP42
Heat shock protein 42

1

3

High-throughput

0.500

High

693767

RUVB2
RuvB-like protein 2

1

5

High-throughput

0.500

High

693714

LST8
Target of rapamycin complex subunit LST8

1

9

High-throughput

0.489

High

587908

PNPP
4-nitrophenylphosphatase

1

0

High-throughput

0.480

High

693702

SHE3
SWI5-dependent HO expression protein 3

1

0

High-throughput

0.480

High

693718

SUM1
Suppressor of mar1-1 protein

1

0

Small-scale

0.480

High

693721

CDT1
Cell division cycle protein CDT1

1

0

Small-scale

0.480

High

693723

ORC5
Origin recognition complex subunit 5

1

0

Small-scale

0.480

High

693729

YG36
Uncharacterized protein YGR126W

1

0

High-throughput

0.480

High

693738

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.480

High

693743

YAP6
AP-1-like transcription factor YAP6

1

0

High-throughput

0.480

High

693747

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.480

High

693749

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.480

High

693750

MDM36
Mitochondrial distribution and morphology protein 36

1

0

Small-scale

0.480

High

693754

AB140
tRNA(Thr)

1

0

High-throughput

0.480

High

693756

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

0

High-throughput

0.480

High

693757

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

High-throughput

0.480

High

693763

NDJ1
Non-disjunction protein 1

1

0

High-throughput

0.480

High

664713

BMH1
Protein BMH1

1

7

Small-scale

0.479

High

693694

BMH2
Protein BMH2

1

7

Small-scale

0.479

High

479434

RS24A
Small ribosomal subunit protein eS24A

1

2

High-throughput

0.457

High

563940

SEC2
Rab guanine nucleotide exchange factor SEC2

1

3

High-throughput

0.457

High

687620

YMC1
Mitochondrial glycine transporter YMC1

1

12

High-throughput

0.457

High

692717

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.457

High

693688

CDC13
Cell division control protein 13

1

1

High-throughput

0.457

High

693691

UGA4
GABA-specific permease

1

2

High-throughput

0.457

High

693700

IST2
Increased sodium tolerance protein 2

1

1

High-throughput

0.457

High

693701

AIM3
Altered inheritance of mitochondria protein 3

1

4

High-throughput

0.457

High

693710

HPH2
Protein HPH2

1

2

High-throughput

0.457

High

693719

BBC1
Myosin tail region-interacting protein MTI1

1

3

High-throughput

0.457

High

693724

NBP1
NAP1-binding protein

1

2

High-throughput

0.457

High

693740

NUM1
Nuclear migration protein NUM1

1

17

Small-scale

0.457

High

693766

ISA2
Iron-sulfur assembly protein 2

1

1

High-throughput

0.457

High

478022

HSP77
Import motor subunit, mitochondrial

1

18

High-throughput

0.445

High

490674

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

510654

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

693744

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

693693

TGL1
Sterol esterase TGL1

1

0

High-throughput

0.279

Low

345233

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

1

0

High-throughput

0.261

Low

693692

SRPR
Signal recognition particle receptor subunit alpha homolog

1

0

High-throughput

0.261

Low

693698

SKG1
Suppressor of lethality of KEX2 GAS1 double null mutant protein 1

1

0

High-throughput

0.261

Low

693711

FCY21
Purine-cytosine permease FCY21

1

0

High-throughput

0.261

Low

693715

PRM10
Pheromone-regulated membrane protein 10

1

0

High-throughput

0.261

Low

693727

MST27
Multicopy suppressor of SEC21 protein 27

1

0

High-throughput

0.261

Low

693733

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.261

Low

693742

YMD7
Uncharacterized protein YML037C

1

0

High-throughput

0.261

Low

693762

ATP14
ATP synthase subunit H, mitochondrial

1

0

High-throughput

0.261

Low

693768

DFM1
DER1-like family member protein 1

1

0

High-throughput

0.261

Low

693752

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024