Protein: GYRB
DNA gyrase subunit B (EC 5.6.2.2) (Type IIA topoisomerase subunit GyrB)

Gene: GYRB
Organism: Escherichia coli K-12
Interactions: 21
UniProt ID: P0AES6

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005694 - chromosome
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

500417

GYRA
DNA gyrase subunit A

2

12

Small-scale

0.759

High

500450

PARE
DNA topoisomerase 4 subunit B

2

6

High-throughput

0.759

High

497088

DEAD
ATP-dependent RNA helicase DeaD

1

0

High-throughput

0.593

High

492342

RF3
Peptide chain release factor RF3

2

2

High-throughput

0.588

High

500451

PHOP
Transcriptional regulatory protein PhoP

1

0

High-throughput

0.586

High

494792

SSRP
SsrA-binding protein

2

0

High-throughput

0.576

High

494737

METK
S-adenosylmethionine synthase

2

0

High-throughput

0.563

High

500452

MOAA
GTP 3',8-cyclase

2

0

High-throughput

0.563

High

500453

METN
Methionine import ATP-binding protein MetN

2

0

High-throughput

0.563

High

500454

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.563

High

495417

YACG
DNA gyrase inhibitor YacG

1

0

High-throughput

0.523

High

493747

RS2
Small ribosomal subunit protein uS2

1

1

High-throughput

0.484

High

494278

RS5
Small ribosomal subunit protein uS5

1

1

High-throughput

0.484

High

500448

EFTU1
Elongation factor Tu 1

1

1

High-throughput

0.484

High

368979

SYGB
Glycine--tRNA ligase beta subunit

1

0

High-throughput

0.464

High

492382

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.464

High

499918

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.464

High

500455

BGLJ
Transcriptional activator protein BglJ

1

0

High-throughput

0.464

High

500447

GCH1L
GTP cyclohydrolase 1 type 2 homolog

1

0

High-throughput

0.458

High

491626

KPRS
Ribose-phosphate pyrophosphokinase

1

1

High-throughput

0.445

High

500449

EFTU2
Elongation factor Tu 2

1

1

High-throughput

0.445

High


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Last updated: 11Aug2025