Interactor 1: GET4 (Q12125)
Golgi to ER traffic protein 4 (Guided entry of tail-anchored proteins 4)
Gene: GET4

Interactor 2: GET3 (Q12154)
ATPase GET3 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Golgi to ER traffic protein 3) (Guided entry of tail-anchored proteins 3)
Gene: GET3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 11283351, 24727835, 20106980, 20554915, 25745174, 28973888, 35189106, 19325107, 20850366
Identification Methods two hybrid pooling approach, pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ArsA_ATPase~GET4
Common GO terms GO:0005829 - cytosol
GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane
GO:0045048 - protein insertion into ER membrane
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 312
Sc

1 354
+ Hs
+ Sp
+ Ce

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Last updated: 15 Jul 2024