Interactor 1: CSN1 (Q13098)
COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)
Gene: GPS1

Interactor 2: CSN7B (Q9H9Q2)
COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b)
Gene: COPS7B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 27833851, 28514442, 32034103, 33961781, 22414063
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, PCI~RPN7
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 491
Hs

1 264
+ Mm
+ Mm
+ Hs
+ Mm
+ At
+ Hs
+ At
+ Hs
+ Mm
+ Hs
+ At
+ Hs
+ Dm
+ Ce
+ Dm
+ Hs
+ An
+ Ce
+ Sp
+ Sc

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Last updated: 15 Jul 2024