Interactor 1: REST (Q13127)
RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor)
Gene: REST

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 17468742
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 6 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1097
Hs

1 488
+ Hs
+ Rn
+ Mm
+ Mm

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Last updated: 15 Jul 2024