HitPredict

Interactor 1: REEP5 (Q00765)
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
Gene: REEP5

Interactor 2: KDSR (Q06136)
3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1)
Gene: KDSR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 332
+	Hs
		1053826 REEP6_HUMAN (4-177): 7.36e-77: 230: 58.05		KDSR_HUMAN (17-332): 1.64e-96: 290: 100.00
+	Hs
		1027245 REEP5_HUMAN (1-189): 3.53e-89: 261: 100.00		DHRS7_HUMAN (18-329): 1.84e-80: 249: 21.73
+	Hs
		1027089 REEP5_HUMAN (1-189): 3.53e-89: 261: 100.00		DHB11_HUMAN (14-281): 1.16e-67: 215: 21.77
+	Hs
		1027025 REEP5_HUMAN (1-189): 3.53e-89: 261: 100.00		DHB12_HUMAN (3-282): 8.12e-61: 198: 23.26
+	Hs
		1279350 REEP6_HUMAN (4-177): 7.36e-77: 230: 58.05		DHB13_HUMAN (12-259): 7.03e-66: 211: 22.71
+	Hs
		1334000 REEP4_HUMAN (56-177): 2.23e-49: 162: 36.07		DHB11_HUMAN (14-281): 1.16e-67: 215: 21.77
+	Hs
		1333973 REEP2_HUMAN (54-176): 1.22e-48: 160: 34.15		DHB11_HUMAN (14-281): 1.16e-67: 215: 21.77