HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: Z518B (Q9C0D4)
Zinc finger protein 518B
Gene: ZNF518B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27705803, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 1074
+	Hs
		983755 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF91_HUMAN (53-697): 0: 661: 13.23
+	Hs
		1027309 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN629_HUMAN (79-706): 0: 613: 11.30
+	Hs
		1027102 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN227_HUMAN (64-698): 0: 568: 10.09
+	Hs
		64140 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN729_HUMAN (106-698): 1.88e-180: 562: 13.79
+	Hs
		1027126 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN615_HUMAN (212-697): 1.47e-133: 423: 10.43
+	Hs
		1027294 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN226_HUMAN (210-697): 1.82e-129: 415: 10.57
+	Hs
		1027217 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN184_HUMAN (2-214): 1.68e-90: 308: 14.09
+	Hs
		728565 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF93_HUMAN (19-390): 1.36e-86: 294: 13.19
+	Hs
		1027052 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		Z518A_HUMAN (921-1069): 7.61e-69: 255: 48.73
+	Mm
		70613 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		Z518A_MOUSE (920-1069): 8.57e-68: 251: 48.10
+	Hs
		563302 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF16_HUMAN (390-697): 8.15e-55: 205: 10.22
+	Hs
		67424 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN850_HUMAN (383-697): 2.39e-53: 205: 9.77
+	Hs
		1027188 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN479_HUMAN (113-371): 5.98e-53: 196: 14.18
+	Hs
		1027027 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN568_HUMAN (3-163): 5.01e-43: 169: 10.78
+	Hs
		1027128 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN565_HUMAN (152-391): 7.17e-42: 164: 14.46
+	Hs
		1027274 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN287_HUMAN (143-390): 2.49e-36: 149: 10.07
+	Hs
		1027201 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN570_HUMAN (2-132): 5.1e-30: 128: 13.14
+	Hs
		1027123 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN283_HUMAN (170-371): 7.55e-24: 110: 10.89
+	Hs
		1027143 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN420_HUMAN (516-698): 2.38e-20: 98.8: 9.14
+	Hs
		549158 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN250_HUMAN (3-104): 3.05e-20: 97.9: 13.21