Interactor 1: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Interactor 2: RASF5 (Q8WWW0)
Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL)
Gene: RASSF5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 24366813, 24981860, 20562859, 21988832, 32707033, 36736316, 24255178, 23455922, 23972470, 20920251, 16892067
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, protein kinase assay, pull down, molecular sieving, x-ray crystallography, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Mst1_SARAH~Nore1-SARAH, C1_1~Pkinase, Nore1-SARAH~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 491
Hs

1 418
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Last updated: 15 Jul 2024