HitPredict

Interactor 1: DNJC3 (Q13217)
DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)
Gene: DNAJC3

Interactor 2: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043066 - negative regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 855
+	Hs
		507978 DNJC3_HUMAN (1-504): 1.15e-88: 282: 100.00		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		1028052 DNJC3_HUMAN (1-504): 1.15e-88: 282: 100.00		NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63
+	Hs
		385407 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		608096 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78
+	Hs
		435627 DNJC3_HUMAN (1-504): 1.15e-88: 282: 100.00		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Hs
		411373 DNJC3_HUMAN (1-504): 1.15e-88: 282: 100.00		INSR_HUMAN (511-849): 1.55e-55: 210: 37.76
+	Hs
		609403 TMTC1_HUMAN (3-364): 7.42e-38: 150: 14.09		FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28
+	Hs
		385615 DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		609590 DNJB9_HUMAN (391-503): 1.35e-35: 134: 35.77		FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28
+	Hs
		1081626 DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98		NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63
+	Hs
		608165 DNJB9_HUMAN (391-503): 1.35e-35: 134: 35.77		FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78
+	Hs
		384341 CDC27_HUMAN (130-487): 4.57e-18: 89.8: 11.83		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		174540 OGT1_HUMAN (13-134): 3.34e-16: 84: 18.03		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		412040 CDC27_HUMAN (130-487): 4.57e-18: 89.8: 11.83		FYN_HUMAN (548-850): 3.85e-99: 320: 35.64
+	Hs
		435695 TTC13_HUMAN (34-337): 1.83e-49: 183: 21.36		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Hs
		411441 TTC13_HUMAN (34-337): 1.83e-49: 183: 21.36		INSR_HUMAN (511-849): 1.55e-55: 210: 37.76
+	Hs
		435780 DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Hs
		435789 DNJB9_HUMAN (391-503): 1.35e-35: 134: 35.77		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Hs
		337363 CDC27_HUMAN (130-487): 4.57e-18: 89.8: 11.83		ABL1_HUMAN (557-846): 9.71e-55: 207: 41.03
+	At
		1352324 TTL3_ARATH (13-183): 5.67e-22: 101: 14.75		BRL2_ARATH (182-489): 1.23e-27: 122: 10.51