HitPredict

Interactor 1: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30126976
Identification Methods	p8 filamentous phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1484 Hs			1 1630
+	Hs
		942337 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42
+	Rn
		677781 NMDE2_RAT (1-1484): 0: 1829: 98.45		DLG4_RAT (812-1187): 3.08e-49: 190: 22.42
+	Mm
		963732 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42
+	Hs
		1028140 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		DLG2_HUMAN (587-879): 1.21e-20: 101: 18.67
+	Hs
		1028145 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Rn
		962666 NMDE2_RAT (1-1484): 0: 1829: 98.45		DLG2_RAT (587-879): 2.66e-21: 103: 18.52
+	Mm
		963769 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		DLG2_MOUSE (587-879): 2.8e-21: 103: 18.52
+	Hs
		1021485 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Rn
		962664 NMDE2_RAT (1-1484): 0: 1829: 98.45		DLG3_RAT (724-947): 3.57e-19: 96.3: 31.23
+	Mm
		936175 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		DLG3_MOUSE (724-947): 3.57e-19: 96.3: 31.23
+	Hs
		1028149 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Mm
		963747 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		LRRC7_MOUSE (386-1092): 1.19e-15: 85.4: 11.74
+	Rn
		962663 NMDE2_RAT (1-1484): 0: 1829: 98.45		DLG1_RAT (679-910): 1.87e-14: 80.9: 22.79
+	Mm
		963751 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		DLG1_MOUSE (678-910): 1.13e-14: 81.7: 22.13
+	Rn
		936853 NMDE2_RAT (1-1484): 0: 1829: 98.45		LRRC7_RAT (629-814): 2.46e-11: 71.2: 21.88
+	Mm
		723533 NMDE1_MOUSE (9-1484): 0: 1516: 52.79		DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42
+	Rn
		677780 NMDE1_RAT (9-1484): 0: 1506: 52.59		DLG4_RAT (812-1187): 3.08e-49: 190: 22.42
+	Rn
		962657 NMDE1_RAT (9-1484): 0: 1506: 52.59		DLG2_RAT (587-879): 2.66e-21: 103: 18.52
+	Rn
		962656 NMDE1_RAT (9-1484): 0: 1506: 52.59		DLG3_RAT (724-947): 3.57e-19: 96.3: 31.23
+	Rn
		962655 NMDE1_RAT (9-1484): 0: 1506: 52.59		DLG1_RAT (679-910): 1.87e-14: 80.9: 22.79