HitPredict

Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: CCL5 (P30882)
C-C motif chemokine 5 (MuRantes) (SIS-delta) (Small-inducible cytokine A5) (T-cell-specific protein RANTES)
Gene: CCL5

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	16707500
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0071346 - cellular response to type II interferon
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 424 Mm			1 91
+	Mm
		660910 IRF8_MOUSE (1-424): 0: 586: 100.00		CCL6_MOUSE (1-90): 9.39e-27: 96.2: 25.23
+	Hs
		1110883 IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47
+	Hs
		562894 IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72		CCL5_HUMAN (1-91): 3.61e-30: 103: 80.22
+	Hs
		1129183 IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47
+	Hs
		1028139 IRF9_HUMAN (5-385): 1.14e-130: 383: 34.01		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47
+	Hs
		562904 IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46		CCL5_HUMAN (1-91): 3.61e-30: 103: 80.22
+	Hs
		1371135 IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47
+	Hs
		533864 IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27		CCL5_HUMAN (1-91): 3.61e-30: 103: 80.22
+	Mm
		583131 IRF1_MOUSE (9-263): 5.51e-75: 238: 25.57		CCL5_MOUSE (1-91): 5.15e-35: 116: 100.00
+	Hs
		533968 IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47