HitPredict

Interactor 1: IRF1 (P15314)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: CCL5 (P30882)
C-C motif chemokine 5 (MuRantes) (SIS-delta) (Small-inducible cytokine A5) (T-cell-specific protein RANTES)
Gene: CCL5

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	15860458, 16707500, 10926836, 21036898
Identification Methods	electrophoretic mobility shift assay, anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 329 Mm			1 91
+	Hs
		533864 IRF1_HUMAN (1-329): 5.35e-176: 491: 84.50		CCL5_HUMAN (1-91): 3.61e-30: 103: 80.22
+	Hs
		533968 IRF1_HUMAN (1-329): 5.35e-176: 491: 84.50		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47
+	Mm
		660920 IRF8_MOUSE (7-199): 2.29e-54: 184: 29.02		CCL5_MOUSE (1-91): 5.15e-35: 116: 100.00
+	Hs
		1028139 IRF9_HUMAN (7-154): 1.01e-60: 200: 33.97		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47
+	Mm
		660910 IRF8_MOUSE (7-199): 2.29e-54: 184: 29.02		CCL6_MOUSE (1-90): 9.39e-27: 96.2: 25.23
+	Hs
		562894 IRF3_HUMAN (1-161): 5.41e-50: 173: 27.95		CCL5_HUMAN (1-91): 3.61e-30: 103: 80.22
+	Hs
		1110883 IRF5_HUMAN (2-125): 5.74e-51: 178: 40.95		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47
+	Hs
		1129183 IRF3_HUMAN (1-161): 5.41e-50: 173: 27.95		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47
+	Hs
		562904 IRF7_HUMAN (4-111): 8.89e-37: 139: 30.77		CCL5_HUMAN (1-91): 3.61e-30: 103: 80.22
+	Hs
		1371135 IRF7_HUMAN (4-111): 8.89e-37: 139: 30.77		CCL19_HUMAN (17-91): 4.24e-21: 81.2: 32.47