Interactor 1: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Interactor 2: 2A5G (Q13362)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-gamma) (PP2A B subunit isoform PR61-gamma) (PP2A B subunit isoform R5-gamma) (Renal carcinoma antigen NY-REN-29)
Gene: PPP2R5C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 0.60 0.598

The method score is based on:

Property Details
Experiments 21460856
Identification Methods enzymatic study, protein kinase assay, anti bait coimmunoprecipitation
Interaction Type direct interaction, phosphorylation reaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006977 - DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007165 - signal transduction
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 3056
Hs

1 524
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024