HitPredict

Interactor 1: TERA (Q01853)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: Vcp

Interactor 2: UBXN1 (Q922Y1)
UBX domain-containing protein 1 (Protein 2B28) (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein) (mY33K)
Gene: UBXN1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	16709668
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CDC48_2~UBX, CDC48_N~UBX
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0034098 - VCP-NPL4-UFD1 AAA ATPase complex GO:0036435 - K48-linked polyubiquitin modification-dependent protein binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 806 Mm			1 297
+	Hs
		934497 TERA_HUMAN (1-806): 0: 774: 100.00		UBXN1_HUMAN (1-297): 3.47e-68: 216: 92.93
+	Hs
		320649 TERA_HUMAN (1-806): 0: 774: 100.00		UBXN7_HUMAN (87-294): 1.52e-42: 154: 16.96
+	Hs
		934930 TERA_HUMAN (1-806): 0: 774: 100.00		UBXN4_HUMAN (47-293): 1.14e-42: 154: 26.74
+	Hs
		935292 TERA_HUMAN (1-806): 0: 774: 100.00		FAF1_HUMAN (82-294): 1.87e-38: 145: 23.94
+	Mm
		931739 TERA_MOUSE (1-806): 0: 774: 100.00		FAF1_MOUSE (82-294): 5.46e-38: 143: 23.94
+	Hs
		122607 TERA_HUMAN (1-806): 0: 774: 100.00		UBXN8_HUMAN (99-294): 3.09e-36: 132: 17.68
+	Hs
		934957 TERA_HUMAN (1-806): 0: 774: 100.00		UBP13_HUMAN (2-155): 2e-33: 131: 23.57
+	Hs
		853451 TERA_HUMAN (1-806): 0: 774: 100.00		UBP5_HUMAN (1-163): 2.54e-32: 128: 26.99
+	Hs
		934345 TERA_HUMAN (1-806): 0: 774: 100.00		UBS3A_HUMAN (5-263): 4.15e-30: 121: 14.92
+	Ce
		759758 TERA1_CAEEL (3-796): 0: 727: 77.13		UBXN4_CAEEL (17-294): 2.45e-47: 166: 23.49
+	Ce
		759759 TERA2_CAEEL (2-783): 0: 725: 79.03		UBXN4_CAEEL (17-294): 2.45e-47: 166: 23.49
+	Ce
		932438 TERA1_CAEEL (3-796): 0: 727: 77.13		UBXN1_CAEEL (4-293): 8.91e-47: 160: 28.39
+	Ce
		932448 TERA2_CAEEL (2-783): 0: 725: 79.03		UBXN1_CAEEL (4-293): 8.91e-47: 160: 28.39
+	Rn
		505016 TERA_RAT (1-806): 0: 775: 99.88		UBX2B_RAT (131-293): 8.66e-26: 106: 14.37
+	Hs
		934623 TERA_HUMAN (1-806): 0: 774: 100.00		UBX2B_HUMAN (99-293): 2.28e-25: 105: 13.15
+	Sc
		679828 CDC48_YEAST (2-806): 0: 740: 67.75		UBX6_YEAST (159-293): 3.81e-32: 124: 24.27
+	Sc
		679621 CDC48_YEAST (2-806): 0: 740: 67.75		UBX7_YEAST (109-293): 3.14e-31: 122: 22.16
+	Sc
		680162 CDC48_YEAST (2-806): 0: 740: 67.75		UBX3_YEAST (106-293): 2.54e-30: 120: 15.05
+	Sp
		1083225 CDC48_SCHPO (9-806): 0: 725: 70.71		YDFB_SCHPO (78-290): 3.3e-28: 110: 24.41