HitPredict

Interactor 1: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Interactor 2: IKZF4 (Q9H2S9)
Zinc finger protein Eos (Ikaros family zinc finger protein 4)
Gene: IKZF4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.900

The method score is based on:

Property Details
Experiments 10218586, 28514442, 10978333, 33961781
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C2H2~zf-C2H2
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
and 3 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 519
Hs

1 585
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024