HitPredict

Interactor 1: S39A6 (Q13433)
Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6)
Gene: SLC39A6

Interactor 2: P2RY8 (Q86VZ1)
P2Y purinoceptor 8 (P2Y8)
Gene: P2RY8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 755 Hs			1 359
+	Hs
		876114 S39A6_HUMAN (1-755): 0: 620: 100.00		PAR2_HUMAN (10-315): 3.78e-82: 257: 35.71
+	Hs
		782420 S39A6_HUMAN (1-755): 0: 620: 100.00		P2RY2_HUMAN (7-345): 1.15e-81: 255: 29.56
+	Hs
		208454 S39A6_HUMAN (1-755): 0: 620: 100.00		OX2R_HUMAN (15-338): 7.54e-69: 224: 16.67
+	Hs
		782488 S39AA_HUMAN (1-755): 4.24e-162: 491: 33.69		P2RY2_HUMAN (7-345): 1.15e-81: 255: 29.56
+	Hs
		849719 S39AA_HUMAN (1-755): 4.24e-162: 491: 33.69		CCR6_HUMAN (12-344): 5.37e-82: 255: 21.22
+	Hs
		126588 S39A6_HUMAN (1-755): 0: 620: 100.00		P2Y10_HUMAN (30-307): 9.64e-30: 118: 34.46
+	Hs
		1202757 S39AA_HUMAN (1-755): 4.24e-162: 491: 33.69		P2RY8_HUMAN (1-359): 1.75e-78: 246: 100.00
+	Hs
		126658 S39AA_HUMAN (1-755): 4.24e-162: 491: 33.69		P2Y10_HUMAN (30-307): 9.64e-30: 118: 34.46
+	Hs
		782422 S39AE_HUMAN (215-749): 1.12e-106: 336: 27.59		P2RY2_HUMAN (7-345): 1.15e-81: 255: 29.56
+	Hs
		429043 S39AE_HUMAN (215-749): 1.12e-106: 336: 27.59		ADRB2_HUMAN (4-332): 2.82e-71: 229: 15.88
+	Hs
		1065466 S39AE_HUMAN (215-749): 1.12e-106: 336: 27.59		P2RY6_HUMAN (26-308): 1.22e-29: 117: 31.33
+	Hs
		1030972 S39A4_HUMAN (229-390): 1.76e-32: 135: 20.73		GPR17_HUMAN (15-331): 1.86e-84: 262: 28.53
+	Hs
		782432 S39A4_HUMAN (229-390): 1.76e-32: 135: 20.73		P2RY2_HUMAN (7-345): 1.15e-81: 255: 29.56
+	Hs
		1160133 S39A4_HUMAN (229-390): 1.76e-32: 135: 20.73		P2RY8_HUMAN (1-359): 1.75e-78: 246: 100.00
+	Hs
		876182 S39AD_HUMAN (292-456): 1.74e-25: 111: 17.06		PAR2_HUMAN (10-315): 3.78e-82: 257: 35.71
+	Hs
		1202721 S39A3_HUMAN (567-740): 2.02e-29: 121: 18.54		P2RY8_HUMAN (1-359): 1.75e-78: 246: 100.00
+	Hs
		429072 S39A4_HUMAN (229-390): 1.76e-32: 135: 20.73		ADRB2_HUMAN (4-332): 2.82e-71: 229: 15.88
+	Hs
		723086 S39AD_HUMAN (292-456): 1.74e-25: 111: 17.06		OPRM_HUMAN (12-356): 5.97e-67: 218: 22.51
+	Hs
		182039 S39A2_HUMAN (555-746): 6.7e-38: 145: 18.78		GPR42_HUMAN (29-308): 7.11e-30: 119: 32.16
+	Hs
		1067558 S39A7_HUMAN (309-627): 7.7e-19: 92.3: 17.19		P2RY6_HUMAN (26-308): 1.22e-29: 117: 31.33