HitPredict

Interactor 1: ADA11 (O75078)
Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)
Gene: ADAM11

Interactor 2: CL12B (Q2HXU8)
C-type lectin domain family 12 member B (Macrophage antigen H)
Gene: CLEC12B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ADAM_CR~Lectin_C
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 769 Hs			1 276
+	Hs
		1034694 ADAM9_HUMAN (54-766): 7.78e-157: 478: 28.75		CL12B_HUMAN (1-276): 7.42e-84: 254: 100.00
+	Hs
		253937 ADA11_HUMAN (1-769): 0: 555: 100.00		NKG2A_HUMAN (3-267): 2.06e-35: 128: 22.47
+	Hs
		644566 ADAM9_HUMAN (54-766): 7.78e-157: 478: 28.75		NKG2A_HUMAN (3-267): 2.06e-35: 128: 22.47
+	Hs
		426866 ADA33_HUMAN (103-712): 1.3e-117: 375: 32.69		ASGR2_HUMAN (2-272): 4.12e-65: 207: 22.19
+	Hs
		314551 ATS2_HUMAN (21-701): 2.06e-96: 327: 18.36		CL12B_HUMAN (1-276): 7.42e-84: 254: 100.00
+	Hs
		1315572 ADA33_HUMAN (103-712): 1.3e-117: 375: 32.69		CLC7A_HUMAN (3-269): 1.07e-53: 176: 27.88
+	Hs
		1265969 ADA21_HUMAN (55-761): 1.2e-123: 388: 25.84		CLC2B_HUMAN (130-266): 8.29e-41: 139: 32.12
+	Hs
		1034765 ADA15_HUMAN (44-712): 1.79e-121: 387: 30.35		CLC2B_HUMAN (130-266): 8.29e-41: 139: 32.12
+	Hs
		152294 ADA10_HUMAN (38-586): 9.04e-77: 265: 20.13		CL12B_HUMAN (1-276): 7.42e-84: 254: 100.00
+	Hs
		1292817 ATS7_HUMAN (41-703): 6.29e-102: 346: 18.39		PGCB_HUMAN (143-272): 3.62e-44: 161: 17.91
+	Hs
		314555 ATS2_HUMAN (21-701): 2.06e-96: 327: 18.36		CL12A_HUMAN (1-271): 1.38e-50: 168: 32.84
+	Hs
		314569 ATS2_HUMAN (21-701): 2.06e-96: 327: 18.36		CLC2B_HUMAN (130-266): 8.29e-41: 139: 32.12
+	Hs
		314541 ATS2_HUMAN (21-701): 2.06e-96: 327: 18.36		NKG2A_HUMAN (3-267): 2.06e-35: 128: 22.47
+	Hs
		314547 ATS2_HUMAN (21-701): 2.06e-96: 327: 18.36		KLRD1_HUMAN (136-267): 1.05e-35: 127: 31.82
+	Mm
		192925 ADA10_MOUSE (34-594): 7.54e-78: 267: 20.84		NCAN_MOUSE (137-272): 1.52e-44: 163: 20.00
+	Hs
		944515 ADA17_HUMAN (65-581): 1.12e-83: 285: 21.22		CLC2B_HUMAN (130-266): 8.29e-41: 139: 32.12
+	Hs
		152315 ADA10_HUMAN (38-586): 9.04e-77: 265: 20.13		CLC2B_HUMAN (130-266): 8.29e-41: 139: 32.12
+	Hs
		152281 ADA10_HUMAN (38-586): 9.04e-77: 265: 20.13		KLRD1_HUMAN (136-267): 1.05e-35: 127: 31.82
+	Hs
		426828 Q08AM2_HUMAN (103-300): 3.68e-39: 156: 27.59		ASGR2_HUMAN (2-272): 4.12e-65: 207: 22.19
+	Hs
		997357 Q08AM2_HUMAN (103-300): 3.68e-39: 156: 27.59		CLC7A_HUMAN (3-269): 1.07e-53: 176: 27.88