Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: STK11 (Q15831)
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)
Gene: STK11

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 25852190, 28514442, 33961781, 32707033, 34591612, 20562859, 14676191, 25036637
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, luminescence based mammalian interactome mapping
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FKBP_C~Pkinase
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0070062 - extracellular exosome
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 457
Hs

1 433
+ Hs
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024