HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: TRI11 (Q96F44)
E3 ubiquitin-protein ligase TRIM11 (EC 2.3.2.27) (Protein BIA1) (RING finger protein 92) (Tripartite motif-containing protein 11)
Gene: TRIM11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27498865
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0030674 - protein-macromolecule adaptor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 468
+	Hs
		584950 SQSTM_HUMAN (1-440): 0: 760: 100.00		RO52_HUMAN (1-465): 1.28e-151: 441: 41.90
+	Hs
		536812 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRI27_HUMAN (1-464): 9.07e-139: 410: 38.28
+	Hs
		1036876 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRIM5_HUMAN (1-458): 3.8e-117: 354: 32.60
+	Hs
		1036706 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRI50_HUMAN (1-453): 2.6e-112: 341: 26.43
+	Mm
		548985 SQSTM_MOUSE (1-440): 0: 731: 90.72		TR30A_MOUSE (1-458): 1.28e-101: 314: 29.28
+	Hs
		1019298 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRI26_HUMAN (1-355): 3.97e-51: 183: 33.86
+	Hs
		584963 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		RO52_HUMAN (1-465): 1.28e-151: 441: 41.90