HitPredict

Interactor 1: MP2K1 (Q02750)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: MAP2K1

Interactor 2: TTC9C (Q8N5M4)
Tetratricopeptide repeat protein 9C (TPR repeat protein 9C)
Gene: TTC9C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 171
+	Hs
		1038290 MP2K1_HUMAN (1-393): 8.09e-126: 369: 100.00		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	At
		1182756 KIN10_ARATH (67-393): 8.47e-123: 366: 19.34		OE64C_ARATH (4-153): 3.77e-32: 122: 18.67
+	Hs
		783570 MP2K2_HUMAN (1-391): 2.16e-123: 364: 79.40		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Hs
		667794 CDK2_HUMAN (65-367): 2.8e-122: 357: 24.60		FKBP4_HUMAN (2-170): 5.52e-35: 128: 23.67
+	Hs
		728217 AKT1_HUMAN (39-389): 4.09e-120: 358: 19.16		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Hs
		1106135 AKT3_HUMAN (30-389): 6.74e-119: 355: 19.51		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Hs
		728585 AKT2_HUMAN (25-389): 1.53e-118: 354: 19.24		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Hs
		1025261 CDK3_HUMAN (65-379): 3.57e-119: 349: 22.12		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Rn
		916731 AKT3_RAT (20-389): 7.46e-112: 337: 21.28		PPP5_RAT (2-163): 7.96e-31: 117: 14.82
+	Hs
		443348 CDK1_HUMAN (65-367): 4.86e-110: 326: 26.45		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Sc
		441205 KAPA_YEAST (2-390): 1.15e-115: 344: 18.69		PPID_YEAST (2-171): 1.04e-21: 91.8: 24.71
+	Hs
		161979 MP2K7_HUMAN (35-375): 7.07e-61: 204: 35.49		FKBP4_HUMAN (2-170): 5.52e-35: 128: 23.67
+	Hs
		124686 MP2K7_HUMAN (35-375): 7.07e-61: 204: 35.49		AIP_HUMAN (2-171): 1.48e-35: 127: 21.05
+	Hs
		161986 MP2K7_HUMAN (35-375): 7.07e-61: 204: 35.49		FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30
+	Hs
		161991 MP2K7_HUMAN (35-375): 7.07e-61: 204: 35.49		FKBP8_HUMAN (2-171): 1.4e-30: 116: 26.47