Interactor 1: EPHA4 (Q03137)
Ephrin type-A receptor 4 (EC 2.7.10.1) (Tyrosine-protein kinase receptor MPK-3) (Tyrosine-protein kinase receptor SEK-1)
Gene: EPHA4
Interactor 2: EPHA4 (Q03137)
Ephrin type-A receptor 4 (EC 2.7.10.1) (Tyrosine-protein kinase receptor MPK-3) (Tyrosine-protein kinase receptor SEK-1)
Gene: EPHA4
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.710 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16977320 |
| Identification Methods | x-ray crystallography, protein kinase assay |
| Interaction Type | direct interaction, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EphA2_TM~PK_Tyr_Ser-Thr, Ephrin_lbd~Ephrin_lbd, Ephrin_lbd~fn3, Ephrin_rec_like~Ephrin_rec_like, fn3~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, SAM_2~SAM_2 |
| Common GO terms | GO:0004672 - protein kinase activity GO:0004714 - transmembrane receptor protein tyrosine kinase activity GO:0005004 - GPI-linked ephrin receptor activity GO:0005005 - transmembrane-ephrin receptor activity GO:0005524 - ATP binding and 67 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025