HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: H90B2 (Q58FF8)
Putative heat shock protein HSP 90-beta 2 (Heat shock protein 90-beta b) (Heat shock protein 90Bb)
Gene: HSP90AB2P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21145461
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 381
+	Hs
		1041725 CUL3_HUMAN (1-768): 0: 951: 100.00		H90B3_HUMAN (1-381): 8.64e-116: 350: 59.04
+	Hs
		1041025 CUL1_HUMAN (18-768): 0: 707: 30.57		H90B2_HUMAN (1-381): 2.81e-170: 482: 100.00
+	Hs
		538226 CUL3_HUMAN (1-768): 0: 951: 100.00		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		1020420 CUL3_HUMAN (1-768): 0: 951: 100.00		TRAP1_HUMAN (135-380): 3.01e-42: 158: 20.45
+	Hs
		438152 CUL3_HUMAN (1-768): 0: 951: 100.00		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		431831 CUL3_HUMAN (1-768): 0: 951: 100.00		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		1041576 CUL3_HUMAN (1-768): 0: 951: 100.00		HS902_HUMAN (87-251): 5.17e-22: 97.7: 54.17
+	Hs
		538227 CUL4A_HUMAN (10-768): 0: 791: 38.32		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		538228 CUL4B_HUMAN (5-768): 0: 779: 36.77		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		538224 CUL1_HUMAN (18-768): 0: 707: 30.57		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		438153 CUL4A_HUMAN (10-768): 0: 791: 38.32		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		1043414 CUL4B_HUMAN (5-768): 0: 779: 36.77		Q6PK50_HUMAN (109-251): 1.1e-33: 130: 87.41
+	Hs
		438154 CUL4B_HUMAN (5-768): 0: 779: 36.77		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		431832 CUL4A_HUMAN (10-768): 0: 791: 38.32		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		431833 CUL4B_HUMAN (5-768): 0: 779: 36.77		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		1043352 CUL4B_HUMAN (5-768): 0: 779: 36.77		HS902_HUMAN (87-251): 5.17e-22: 97.7: 54.17
+	Hs
		438150 CUL1_HUMAN (18-768): 0: 707: 30.57		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		431829 CUL1_HUMAN (18-768): 0: 707: 30.57		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		1040982 CUL1_HUMAN (18-768): 0: 707: 30.57		HS902_HUMAN (87-251): 5.17e-22: 97.7: 54.17
+	Hs
		431830 CUL2_HUMAN (30-768): 0: 672: 26.17		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54