Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: SPOPL (Q6IQ16)
Speckle-type POZ protein-like (HIB homolog 2) (Roadkill homolog 2)
Gene: SPOPL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 22632832
Identification Methods isothermal titration calorimetry
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BTB~Cullin
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0031625 - ubiquitin protein ligase binding
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 768
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024