HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: KCTD6 (Q8NC69)
BTB/POZ domain-containing protein KCTD6 (KCASH3 protein) (Potassium channel tetramerization domain-containing protein 6)
Gene: KCTD6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	0.60	0.760

Property	Details
Experiments	25974686, 27621083, 33961781, 25416956, 26334369, 28514442, 32296183, 35563538, 21145461, 22573887, unassigned1304, 27152988
Identification Methods	pull down, affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification, anti tag coimmunoprecipitation, electron microscopy
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 237
+	Hs
		1042523 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD3_HUMAN (6-213): 1.49e-56: 184: 25.47
+	Hs
		1041533 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD2_HUMAN (6-213): 4.96e-52: 172: 24.88
+	Hs
		1042165 CUL3_HUMAN (1-768): 0: 951: 100.00		BACD1_HUMAN (11-213): 5.07e-51: 170: 25.00
+	Hs
		1041881 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD1_HUMAN (10-235): 6.1e-51: 167: 28.69
+	Hs
		1042675 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD5_HUMAN (8-197): 8.63e-49: 161: 26.80
+	Hs
		1041584 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD2_HUMAN (6-197): 9.14e-48: 160: 23.35
+	Hs
		1042035 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD17_HUMAN (12-191): 2.51e-46: 157: 28.96
+	Hs
		1041891 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD9_HUMAN (5-217): 1.4e-44: 155: 23.50
+	Hs
		1042309 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD7_HUMAN (10-209): 2.26e-45: 154: 30.59
+	Hs
		1041705 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD21_HUMAN (10-157): 4.44e-43: 147: 49.33
+	Hs
		1041839 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD18_HUMAN (12-145): 5.67e-41: 146: 34.33
+	Hs
		1042934 CUL3_HUMAN (1-768): 0: 951: 100.00		KCTD3_HUMAN (10-156): 1.77e-37: 140: 32.65
+	Hs
		1042242 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD12_HUMAN (9-105): 2.76e-37: 134: 43.43
+	Hs
		1041790 CUL3_HUMAN (1-768): 0: 951: 100.00		KCD11_HUMAN (37-107): 1.34e-16: 77.8: 54.67
+	Hs
		1042096 CUL3_HUMAN (1-768): 0: 951: 100.00		SHKB1_HUMAN (14-105): 1.44e-13: 71.2: 44.57
+	Ce
		1088879 CUL3_CAEEL (4-768): 0: 792: 48.08		Q18986_CAEEL (10-225): 8.44e-46: 154: 23.50
+	Ce
		1088878 CUL3_CAEEL (4-768): 0: 792: 48.08		Q18776_CAEEL (6-196): 2.96e-44: 151: 27.46
+	Ce
		954547 CUL3_CAEEL (4-768): 0: 792: 48.08		P91563_CAEEL (10-179): 8.86e-44: 149: 24.12
+	Ce
		184054 CUL3_CAEEL (4-768): 0: 792: 48.08		O16612_CAEEL (9-171): 5.7e-43: 146: 26.06
+	Ce
		109385 CUL3_CAEEL (4-768): 0: 792: 48.08		H2KY83_CAEEL (9-169): 1.56e-42: 144: 26.83