HitPredict

Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Interactor 2: CRNL1 (Q9BZJ0)
Crooked neck-like protein 1 (Crooked neck homolog) (hCrn)
Gene: CRNKL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26030138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1493 Hs			1 848
+	Hs
		1132954 CHD4_HUMAN (317-1426): 0: 725: 19.25		CRNL1_HUMAN (1-848): 0: 583: 100.00
+	Hs
		1042881 ERCC6_HUMAN (1-1493): 0: 1167: 100.00		CTR9_HUMAN (65-456): 5.76e-24: 110: 9.80
+	Hs
		1042929 ERCC6_HUMAN (1-1493): 0: 1167: 100.00		SYF1_HUMAN (470-769): 5.91e-12: 71.6: 18.24
+	Hs
		321510 CHD3_HUMAN (317-1445): 0: 747: 19.86		PRP6_HUMAN (71-843): 1.84e-69: 249: 14.39
+	Hs
		321530 CHD4_HUMAN (317-1426): 0: 725: 19.25		PRP6_HUMAN (71-843): 1.84e-69: 249: 14.39
+	Hs
		321469 SMCA2_HUMAN (228-1388): 0: 684: 18.32		PRP6_HUMAN (71-843): 1.84e-69: 249: 14.39
+	Hs
		1088344 CHD3_HUMAN (317-1445): 0: 747: 19.86		RRP5_HUMAN (464-791): 3.1e-35: 147: 14.50
+	Hs
		1130734 CHD4_HUMAN (317-1426): 0: 725: 19.25		RRP5_HUMAN (464-791): 3.1e-35: 147: 14.50
+	Hs
		1088403 CHD3_HUMAN (317-1445): 0: 747: 19.86		CTR9_HUMAN (65-456): 5.76e-24: 110: 9.80
+	Hs
		1243862 CHD8_HUMAN (177-1471): 0: 739: 16.90		CTR9_HUMAN (65-456): 5.76e-24: 110: 9.80
+	Hs
		109577 CHD8_HUMAN (177-1471): 0: 739: 16.90		G5EA36_HUMAN (312-638): 2.63e-22: 105: 10.24
+	Hs
		718635 CHD8_HUMAN (177-1471): 0: 739: 16.90		CDC27_HUMAN (312-638): 3.13e-22: 104: 10.24
+	Hs
		1132768 CHD4_HUMAN (317-1426): 0: 725: 19.25		CTR9_HUMAN (65-456): 5.76e-24: 110: 9.80
+	Hs
		1132990 CHD4_HUMAN (317-1426): 0: 725: 19.25		SYF1_HUMAN (470-769): 5.91e-12: 71.6: 18.24
+	Hs
		194531 SMCA4_HUMAN (228-1299): 0: 681: 20.36		KDM6A_HUMAN (133-603): 2.73e-23: 108: 8.45
+	Sc
		744343 CHD1_YEAST (381-1426): 0: 714: 20.19		RRP5_YEAST (211-449): 5.55e-12: 72.2: 14.75
+	Dm
		356720 CHDM_DROME (281-1427): 0: 668: 17.51		SUF_DROME (163-528): 3.95e-24: 110: 14.63
+	Hs
		718628 SMRCD_HUMAN (4-1008): 0: 628: 21.13		CDC27_HUMAN (312-638): 3.13e-22: 104: 10.24