HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: WDR5B (Q86VZ2)
WD repeat-containing protein 5B
Gene: WDR5B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 330
+	Hs
		903209 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		1043499 CUL4B_HUMAN (1-913): 0: 1184: 100.00		FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40
+	Hs
		245601 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1X_HUMAN (120-330): 1.23e-48: 173: 27.56
+	Hs
		1043562 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1R_HUMAN (120-330): 3.57e-48: 170: 28.00
+	Hs
		1043469 CUL4B_HUMAN (1-913): 0: 1184: 100.00		POC1B_HUMAN (154-330): 5.19e-47: 166: 20.90
+	Hs
		1043385 CUL4B_HUMAN (1-913): 0: 1184: 100.00		SMU1_HUMAN (39-326): 3.4e-36: 138: 29.70
+	Hs
		1043509 CUL4B_HUMAN (1-913): 0: 1184: 100.00		SNR40_HUMAN (197-329): 1.9e-28: 114: 27.61
+	Hs
		903208 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		1043085 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5B_HUMAN (2-282): 1.14e-90: 275: 29.97
+	Hs
		903207 CUL3_HUMAN (186-913): 0: 853: 37.19		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		1043114 CUL4A_HUMAN (161-913): 0: 955: 81.83		POC1B_HUMAN (154-330): 5.19e-47: 166: 20.90
+	Hs
		792982 CUL4A_HUMAN (161-913): 0: 955: 81.83		LIS1_HUMAN (1-113): 3.92e-31: 122: 20.30
+	Hs
		1043157 CUL4A_HUMAN (161-913): 0: 955: 81.83		SNR40_HUMAN (197-329): 1.9e-28: 114: 27.61
+	Hs
		903206 CUL1_HUMAN (213-913): 0: 778: 30.16		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		197016 CUL3_HUMAN (186-913): 0: 853: 37.19		PRP4_HUMAN (125-330): 6.22e-50: 175: 22.43
+	Hs
		1042101 CUL3_HUMAN (186-913): 0: 853: 37.19		POC1B_HUMAN (154-330): 5.19e-47: 166: 20.90
+	Hs
		209433 CUL3_HUMAN (186-913): 0: 853: 37.19		PLRG1_HUMAN (158-328): 2.42e-40: 149: 28.66
+	Hs
		1041692 CUL3_HUMAN (186-913): 0: 853: 37.19		SMU1_HUMAN (39-326): 3.4e-36: 138: 29.70
+	Hs
		1042655 CUL3_HUMAN (186-913): 0: 853: 37.19		NLE1_HUMAN (193-329): 6.37e-33: 128: 22.38
+	Hs
		1041647 CUL3_HUMAN (186-913): 0: 853: 37.19		TAF5_HUMAN (159-326): 3.6e-11: 66.2: 24.75