Protein: UNC5B
Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1)

Gene: UNC5B
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q8IZJ1

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0005042 - netrin receptor activity
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0033564 - anterior/posterior axon guidance

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862073

DAPK1
Death-associated protein kinase 1

2

8

Small-scale

0.757

High

317792

NET1
Netrin-1

2

10

Small-scale

0.754

High

1224467

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

2

8

High-throughput

0.726

High

1224475

FLRT3
Leucine-rich repeat transmembrane protein FLRT3

1

20

Small-scale

0.647

High

171312

EPHB6
Ephrin type-B receptor 6

1

11

High-throughput

0.618

High

385149

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

411434

INSR
Insulin receptor

1

20

High-throughput

0.618

High

435694

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.618

High

508096

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

608042

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

665499

EPHA8
Ephrin type-A receptor 8

1

13

High-throughput

0.618

High

665628

EPHB2
Ephrin type-B receptor 2

1

11

High-throughput

0.618

High

729310

VGFR3
Vascular endothelial growth factor receptor 3

1

14

High-throughput

0.618

High

872459

EPHA5
Ephrin type-A receptor 5

1

14

High-throughput

0.618

High

872674

EPHA4
Ephrin type-A receptor 4

1

12

High-throughput

0.618

High

968321

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

High-throughput

0.618

High

968431

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.618

High

1072543

EPHA7
Ephrin type-A receptor 7

1

9

High-throughput

0.618

High

1081529

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.618

High

1224465

NEO1
Neogenin

1

9

Small-scale

0.618

High

1224474

TREM2
Triggering receptor expressed on myeloid cells 2

1

0

Small-scale

0.614

High

350330

RASK
GTPase KRas

2

13

High-throughput

0.584

High

507116

LAMP1
Lysosome-associated membrane glycoprotein 1

2

0

High-throughput

0.559

High

672445

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

2

Small-scale

0.552

High

608238

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

0

High-throughput

0.493

High

1224461

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.489

High

1224478

FBX2
F-box only protein 2

1

5

High-throughput

0.489

High

178652

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

205650

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

212923

STX6
Syntaxin-6

1

3

High-throughput

0.479

High

279631

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

348774

RASN
GTPase NRas

1

14

High-throughput

0.479

High

349465

RASH
GTPase HRas

1

11

High-throughput

0.479

High

433884

LYN
Tyrosine-protein kinase Lyn

1

6

High-throughput

0.479

High

434237

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.479

High

564606

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

567162

CXA1
Gap junction alpha-1 protein

1

14

High-throughput

0.479

High

577041

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

7

High-throughput

0.479

High

592365

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.479

High

670109

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

852549

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

892478

RAC3
Ras-related C3 botulinum toxin substrate 3

1

15

High-throughput

0.479

High

894201

CDC42
Cell division control protein 42 homolog

1

18

High-throughput

0.479

High

900676

RHOA
Transforming protein RhoA

1

16

High-throughput

0.479

High

901199

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

912988

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

915821

RHOB
Rho-related GTP-binding protein RhoB

1

18

High-throughput

0.479

High

925426

RAC1
Ras-related C3 botulinum toxin substrate 1

1

15

High-throughput

0.479

High

930919

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

3

Small-scale

0.479

High

974916

CAV1
Caveolin-1

1

6

High-throughput

0.479

High

1017701

STX4
Syntaxin-4

1

4

High-throughput

0.479

High

1070289

RAB35
Ras-related protein Rab-35

1

6

High-throughput

0.479

High

1076656

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1084090

OCLN
Occludin

1

5

High-throughput

0.479

High

1151962

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1153705

STYK1
Tyrosine-protein kinase STYK1

1

13

High-throughput

0.479

High

1183457

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1224460

CXD3
Gap junction delta-3 protein

1

14

High-throughput

0.479

High

1224462

CIP2A
Protein CIP2A

1

1

Small-scale

0.479

High

1224463

PARD3
Partitioning defective 3 homolog

1

16

High-throughput

0.479

High

1224464

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1224469

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1224470

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1224471

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1224479

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.479

High

132531

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

169526

BET1
BET1 homolog

1

3

High-throughput

0.437

High

305537

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

614073

TBG1
Tubulin gamma-1 chain

1

9

High-throughput

0.437

High

654528

CALX
Calnexin

1

4

High-throughput

0.437

High

1188291

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.437

High

1203764

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1224466

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1224468

FMNL2
Formin-like protein 2

1

1

High-throughput

0.437

High

1224473

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.437

High

1224477

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

3

High-throughput

0.437

High

1224472

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1224476

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024