HitPredict

Interactor 1: HMO1 (Q03973)
High mobility group protein 1 (High spontaneous mutagenesis protein 2)
Gene: HMO1

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.648

Property	Details
Experiments	18719252, 15590687, 23403034
Identification Methods	two hybrid, affinity chromatography technology, protein complementation assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 246 Sc			1 101
+	Hs
		964352 PB1_HUMAN (23-216): 2.04e-31: 124: 15.98		SUMO2_HUMAN (9-98): 2.33e-36: 120: 42.86
+	Hs
		964242 SSRP1_HUMAN (21-234): 1.05e-28: 115: 18.34		SUMO2_HUMAN (9-98): 2.33e-36: 120: 42.86
+	Hs
		776166 SOX6_HUMAN (38-186): 5.19e-26: 108: 13.91		SUMO2_HUMAN (9-98): 2.33e-36: 120: 42.86
+	Sc
		752996 IXR1_YEAST (86-196): 1.72e-22: 97.7: 22.52		SMT3_YEAST (1-101): 1.8e-40: 130: 100.00
+	Hs
		991308 SSRP1_HUMAN (21-234): 1.05e-28: 115: 18.34		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		872146 SOX2_HUMAN (79-194): 2.98e-25: 103: 17.24		SUMO2_HUMAN (9-98): 2.33e-36: 120: 42.86
+	Hs
		107794 SOX5_HUMAN (20-186): 2.65e-25: 105: 15.61		SUMO5_HUMAN (1-98): 5e-35: 117: 43.88
+	Hs
		872179 SOX2_HUMAN (79-194): 2.98e-25: 103: 17.24		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		659196 SP100_HUMAN (83-194): 1.55e-14: 74.6: 20.54		SUMO2_HUMAN (9-98): 2.33e-36: 120: 42.86
+	Hs
		107793 SP100_HUMAN (83-194): 1.55e-14: 74.6: 20.54		SUMO5_HUMAN (1-98): 5e-35: 117: 43.88
+	Hs
		659194 SP100_HUMAN (83-194): 1.55e-14: 74.6: 20.54		SUMO3_HUMAN (9-98): 2.25e-34: 115: 43.96
+	Hs
		659202 SP100_HUMAN (83-194): 1.55e-14: 74.6: 20.54		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Dm
		356328 HMGD_DROME (104-179): 8.09e-09: 54.1: 19.74		O97102_DROME (13-99): 2.67e-35: 117: 43.18