Interactor 1: TF2H2 (Q13888)
General transcription factor IIH subunit 2 (Basic transcription factor 2 44 kDa subunit) (BTF2 p44) (General transcription factor IIH polypeptide 2) (TFIIH basal transcription factor complex p44 subunit)
Gene: GTF2H2

Interactor 2: TF2H4 (Q92759)
General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit)
Gene: GTF2H4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.743

The method score is based on:

Property Details
Experiments 26340423, 33961781, 28977422, 24981860, 11062469, 19172752, 19934020
Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000438 - core TFIIH complex portion of holo TFIIH complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
and 5 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 395
Hs

1 462
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024