HitPredict

Interactor 1: CDK13 (Q14004)
Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)
Gene: CDK13

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1512 Hs			1 444
+	Hs
		428202 CDK13_HUMAN (1-1512): 0: 912: 100.00		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		1037223 CDK13_HUMAN (1-1512): 0: 912: 100.00		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		933805 CDK13_HUMAN (1-1512): 0: 912: 100.00		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		381203 CDK13_HUMAN (1-1512): 0: 912: 100.00		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		625344 CDK2_HUMAN (702-1004): 6.13e-140: 433: 41.45		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		625420 CDK2_HUMAN (702-1004): 6.13e-140: 433: 41.45		TBB2A_HUMAN (1-430): 0: 715: 90.00
+	Rn
		600380 MK03_RAT (696-1046): 4.78e-134: 421: 31.07		TBB5_RAT (1-429): 0: 720: 89.74
+	Rn
		600406 MK03_RAT (696-1046): 4.78e-134: 421: 31.07		TBB3_RAT (1-442): 0: 718: 86.20
+	Rn
		600385 MK03_RAT (696-1046): 4.78e-134: 421: 31.07		TBB2A_RAT (1-430): 0: 715: 90.00
+	Hs
		414682 CDK1_HUMAN (702-1003): 1.17e-132: 414: 39.80		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		428094 CDK9_HUMAN (702-1030): 1.93e-122: 389: 44.78		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		841644 CDK9_HUMAN (702-1030): 1.93e-122: 389: 44.78		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		841709 CDK9_HUMAN (702-1030): 1.93e-122: 389: 44.78		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		841869 CDK9_HUMAN (702-1030): 1.93e-122: 389: 44.78		TBB6_HUMAN (1-432): 0: 715: 86.81