HitPredict

Interactor 1: TLE2 (Q04725)
Transducin-like enhancer protein 2 (Enhancer of split groucho-like protein 2) (ESG2)
Gene: TLE2

Interactor 2: PHLP (Q13371)
Phosducin-like protein (PHLP)
Gene: PDCL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Phosducin~WD40
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 743 Hs			1 301
+	Hs
		1047935 TLE2_HUMAN (1-743): 1.19e-176: 525: 100.00		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		983470 GBB1_HUMAN (447-739): 3.4e-90: 287: 18.54		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		163636 GNB5_HUMAN (446-739): 1.51e-86: 280: 20.46		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		1103638 POC1A_HUMAN (490-742): 3.98e-75: 250: 16.02		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		1103660 GBB4_HUMAN (484-742): 1e-57: 201: 16.05		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Bt
		624601 GBB1_BOVIN (447-739): 3.4e-90: 287: 18.54		PHOS_BOVIN (51-291): 6.22e-75: 231: 46.89
+	Hs
		983572 GBB1_HUMAN (447-739): 3.4e-90: 287: 18.54		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		1334170 POC1A_HUMAN (490-742): 3.98e-75: 250: 16.02		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		597358 GBB3_HUMAN (659-742): 9.55e-14: 75.2: 18.82		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		984101 GBB2_HUMAN (659-742): 2.09e-13: 74.1: 17.65		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		155783 POC1A_HUMAN (490-742): 3.98e-75: 250: 16.02		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85
+	Dm
		684604 GBB1_DROME (430-617): 8.37e-32: 128: 20.00		PHLP1_DROME (1-277): 9.43e-89: 267: 44.41
+	Hs
		300142 TLE5_HUMAN (1-185): 2.39e-91: 285: 62.89		GLRX3_HUMAN (171-250): 2.54e-20: 91: 23.46
+	Ce
		604389 GBB1_CAEEL (430-617): 9.8e-34: 134: 18.95		Q9U1X7_CAEEL (4-269): 1.7e-59: 192: 27.14
+	Hs
		984274 GBB2_HUMAN (659-742): 2.09e-13: 74.1: 17.65		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		155747 GBB2_HUMAN (659-742): 2.09e-13: 74.1: 17.65		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85