HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: RIPP2 (Q5TAB7)
Protein ripply2
Gene: RIPPLY2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 772 Hs			1 128
+	Hs
		1047834 TLE1_HUMAN (1-772): 0: 553: 77.96		RIPP2_HUMAN (1-128): 5.89e-79: 230: 100.00
+	Hs
		1048165 TLE4_HUMAN (1-772): 0: 541: 80.52		RIPP2_HUMAN (1-128): 5.89e-79: 230: 100.00
+	Hs
		1047959 TLE3_HUMAN (1-772): 0: 597: 100.00		RIPP1_HUMAN (28-112): 8.46e-38: 126: 38.82
+	Hs
		943469 TLE3_HUMAN (1-772): 0: 597: 100.00		DSCR6_HUMAN (37-117): 1.58e-36: 124: 38.27
+	Hs
		1047913 TLE2_HUMAN (1-772): 5.37e-150: 458: 62.35		RIPP2_HUMAN (1-128): 5.89e-79: 230: 100.00
+	Hs
		1047805 TLE1_HUMAN (1-772): 0: 553: 77.96		RIPP1_HUMAN (28-112): 8.46e-38: 126: 38.82
+	Hs
		943467 TLE1_HUMAN (1-772): 0: 553: 77.96		DSCR6_HUMAN (37-117): 1.58e-36: 124: 38.27
+	Hs
		1048152 TLE4_HUMAN (1-772): 0: 541: 80.52		RIPP1_HUMAN (28-112): 8.46e-38: 126: 38.82
+	Hs
		943470 TLE4_HUMAN (1-772): 0: 541: 80.52		DSCR6_HUMAN (37-117): 1.58e-36: 124: 38.27
+	Xl
		205898 TLE4_XENLA (1-772): 1.31e-170: 512: 79.61		BOWL_XENLA (36-118): 1.69e-39: 131: 48.19
+	Hs
		1047898 TLE2_HUMAN (1-772): 5.37e-150: 458: 62.35		RIPP1_HUMAN (28-112): 8.46e-38: 126: 38.82
+	Hs
		943468 TLE2_HUMAN (1-772): 5.37e-150: 458: 62.35		DSCR6_HUMAN (37-117): 1.58e-36: 124: 38.27
+	Hs
		1206454 Q5JSZ1_HUMAN (1-202): 3.79e-114: 346: 72.69		RIPP2_HUMAN (1-128): 5.89e-79: 230: 100.00
+	Hs
		1061736 TLE5_HUMAN (1-200): 1.39e-100: 310: 62.19		RIPP2_HUMAN (1-128): 5.89e-79: 230: 100.00
+	Hs
		1212330 Q5T3G3_HUMAN (1-232): 5.32e-94: 294: 67.49		RIPP2_HUMAN (1-128): 5.89e-79: 230: 100.00
+	Hs
		1068904 Q5JSZ1_HUMAN (1-202): 3.79e-114: 346: 72.69		RIPP1_HUMAN (28-112): 8.46e-38: 126: 38.82
+	Hs
		1061675 TLE5_HUMAN (1-200): 1.39e-100: 310: 62.19		RIPP1_HUMAN (28-112): 8.46e-38: 126: 38.82
+	Hs
		943471 TLE5_HUMAN (1-200): 1.39e-100: 310: 62.19		DSCR6_HUMAN (37-117): 1.58e-36: 124: 38.27
+	Hs
		1068906 Q5T3G3_HUMAN (1-232): 5.32e-94: 294: 67.49		RIPP1_HUMAN (28-112): 8.46e-38: 126: 38.82