HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: STRAB (Q9C0K7)
STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2)
Gene: STRADB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 418
+	Hs
		625579 TCPH_HUMAN (4-532): 0: 591: 34.08		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		625349 TCPB_HUMAN (1-535): 0: 586: 100.00		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		1306668 TCPH_HUMAN (4-532): 0: 591: 34.08		STRAB_HUMAN (1-418): 5.39e-125: 369: 98.33
+	Hs
		415042 TCPH_HUMAN (4-532): 0: 591: 34.08		CDK1_HUMAN (55-374): 1.01e-123: 361: 20.56
+	Hs
		625228 TCPG_HUMAN (3-532): 0: 561: 28.33		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		826872 TCPG_HUMAN (3-532): 0: 561: 28.33		STRAB_HUMAN (1-418): 5.39e-125: 369: 98.33
+	Hs
		625220 TCPE_HUMAN (1-528): 0: 541: 32.29		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		960322 TCPH_HUMAN (4-532): 0: 591: 34.08		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		1023098 TCPH_HUMAN (4-532): 0: 591: 34.08		STK4_HUMAN (58-373): 3.33e-104: 318: 25.00
+	Hs
		943194 TCPB_HUMAN (1-535): 0: 586: 100.00		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		414817 TCPE_HUMAN (1-528): 0: 541: 32.29		CDK1_HUMAN (55-374): 1.01e-123: 361: 20.56
+	Hs
		826737 TCPG_HUMAN (3-532): 0: 561: 28.33		STRAA_HUMAN (20-388): 1.16e-113: 341: 46.61
+	Hs
		1306764 TCPH_HUMAN (4-532): 0: 591: 34.08		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Hs
		1306717 TCPH_HUMAN (4-532): 0: 591: 34.08		STK26_HUMAN (58-390): 2.83e-99: 303: 26.13
+	Hs
		943563 TCPB_HUMAN (1-535): 0: 586: 100.00		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Hs
		826623 TCPG_HUMAN (3-532): 0: 561: 28.33		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Dm
		1249855 Q9W392_DROME (4-535): 0: 568: 70.73		HIPPO_DROME (38-381): 1.14e-99: 312: 22.97
+	Hs
		826636 TCPG_HUMAN (3-532): 0: 561: 28.33		STK4_HUMAN (58-373): 3.33e-104: 318: 25.00
+	Hs
		826963 TCPG_HUMAN (3-532): 0: 561: 28.33		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Hs
		821173 TCPE_HUMAN (1-528): 0: 541: 32.29		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77