HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 772 Hs			1 1235
+	Hs
		903330 TLE3_HUMAN (1-772): 0: 597: 100.00		SMCA4_HUMAN (1057-1208): 7.29e-19: 95.5: 13.84
+	Hs
		1048052 TLE3_HUMAN (1-772): 0: 597: 100.00		CBP_HUMAN (105-563): 8.91e-10: 65.7: 7.96
+	Hs
		1047958 TLE3_HUMAN (1-772): 0: 597: 100.00		EP300_HUMAN (150-707): 9.24e-09: 62.4: 8.45
+	Sp
		268353 NLE1_SCHPO (223-687): 5.91e-74: 250: 11.31		YK82_SCHPO (843-1204): 9.27e-26: 116: 13.90
+	Mm
		74304 TLE6_MOUSE (473-772): 8e-46: 174: 33.66		EP300_MOUSE (807-1211): 5.16e-30: 131: 15.12
+	Hs
		1450947 NLE1_HUMAN (651-771): 5.85e-34: 138: 16.92		BAZ2A_HUMAN (125-815): 1.94e-34: 146: 11.39
+	Hs
		965132 WDR5_HUMAN (238-560): 1.08e-30: 125: 8.46		KAT2B_HUMAN (1075-1209): 2.95e-37: 154: 23.70
+	Dm
		1463919 WDS_DROME (284-563): 3.5e-31: 127: 8.68		Q9VTZ1_DROME (683-811): 1.26e-36: 151: 23.88
+	Hs
		639703 WDR5_HUMAN (238-560): 1.08e-30: 125: 8.46		TAF1_HUMAN (1002-1220): 4.19e-22: 106: 15.32
+	Hs
		1387623 SNR40_HUMAN (509-677): 5.37e-09: 60.8: 26.52		BAZ2A_HUMAN (125-815): 1.94e-34: 146: 11.39
+	Hs
		965131 WDR5_HUMAN (238-560): 1.08e-30: 125: 8.46		KAT2A_HUMAN (684-810): 1.1e-12: 74.9: 17.32
+	Mm
		965405 WDR5_MOUSE (238-560): 1.08e-30: 125: 8.46		KAT2A_MOUSE (684-810): 1.09e-12: 74.9: 17.32
+	Hs
		180894 SNR40_HUMAN (509-677): 5.37e-09: 60.8: 26.52		TIF1A_HUMAN (846-1228): 2.48e-31: 135: 14.11
+	Hs
		965128 WDR5_HUMAN (238-560): 1.08e-30: 125: 8.46		CBP_HUMAN (105-563): 8.91e-10: 65.7: 7.96
+	Hs
		964892 WDR5_HUMAN (238-560): 1.08e-30: 125: 8.46		EP300_HUMAN (150-707): 9.24e-09: 62.4: 8.45
+	Hs
		903453 SNR40_HUMAN (509-677): 5.37e-09: 60.8: 26.52		SMCA4_HUMAN (1057-1208): 7.29e-19: 95.5: 13.84