HitPredict

Interactor 1: TRI14 (Q14142)
Tripartite motif-containing protein 14
Gene: TRIM14

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 24379373, 31070748
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006954 - inflammatory response
GO:0045087 - innate immune response
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 442
Hs

1 419
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Last updated: 15 Jul 2024