Protein: PLXA3
Plexin-A3 (Plexin-4) (Semaphorin receptor SEX)

Gene: PLXA3, PLXNA3
Organism: Homo sapiens
Interactions: 102
UniProt ID: P51805

Gene Ontology (top 5):
GO:0002116 - semaphorin receptor complex
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0007416 - synapse assembly
GO:0008045 - motor neuron axon guidance

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

351672

SG1D1
Secretoglobin family 1D member 1

3

6

High-throughput

0.765

High

731828

CEAM8
Cell adhesion molecule CEACAM8

1

4

High-throughput

0.691

High

907936

SIRPD
Signal-regulatory protein delta

1

2

High-throughput

0.691

High

907948

BTNL2
Butyrophilin-like protein 2

1

15

High-throughput

0.691

High

568044

HLAE
HLA class I histocompatibility antigen, alpha chain E

3

7

High-throughput

0.667

High

286526

SG2A1
Mammaglobin-B

1

3

High-throughput

0.618

High

907900

SG2A2
Mammaglobin-A

1

3

High-throughput

0.618

High

907922

CA054
Uncharacterized protein C1orf54

2

9

High-throughput

0.549

High

907949

FBX2
F-box only protein 2

2

16

High-throughput

0.549

High

380414

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

15

High-throughput

0.536

High

607355

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

7

High-throughput

0.536

High

688537

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

17

High-throughput

0.536

High

907895

IL5RA
Interleukin-5 receptor subunit alpha

1

12

High-throughput

0.536

High

907896

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

3

High-throughput

0.536

High

907902

PTC1
Protein patched homolog 1

1

7

High-throughput

0.536

High

907908

EPHA7
Ephrin type-A receptor 7

1

13

High-throughput

0.536

High

907914

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

907919

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

3

High-throughput

0.536

High

907925

CLC2B
C-type lectin domain family 2 member B

1

16

High-throughput

0.536

High

907929

T106A
Transmembrane protein 106A

1

8

High-throughput

0.536

High

907931

ASIC4
Acid-sensing ion channel 4

1

4

High-throughput

0.536

High

907941

PAR6A
Partitioning defective 6 homolog alpha

1

9

High-throughput

0.536

High

907952

PCDB3
Protocadherin beta-3

1

6

High-throughput

0.536

High

907953

PCDBF
Protocadherin beta-15

1

6

High-throughput

0.536

High

907943

TMPS4
Transmembrane protease serine 4

1

14

High-throughput

0.515

High

907928

TRI63
E3 ubiquitin-protein ligase TRIM63

1

11

High-throughput

0.494

High

907935

TRI55
Tripartite motif-containing protein 55

1

11

High-throughput

0.494

High

85965

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

11

High-throughput

0.489

High

154806

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

3

High-throughput

0.489

High

171683

GAK
Cyclin-G-associated kinase

1

4

High-throughput

0.489

High

257098

CCD22
Coiled-coil domain-containing protein 22

1

2

High-throughput

0.489

High

337167

APOM
Apolipoprotein M

1

1

High-throughput

0.489

High

342525

LY86
Lymphocyte antigen 86

1

5

High-throughput

0.489

High

388704

C1QB
Complement C1q subcomponent subunit B

1

10

High-throughput

0.489

High

455639

KLK3
Prostate-specific antigen

1

17

High-throughput

0.489

High

547989

PSPC
Surfactant protein C

1

8

High-throughput

0.489

High

597791

CRIS2
Cysteine-rich secretory protein 2

1

4

High-throughput

0.489

High

647336

IDS
Iduronate 2-sulfatase

1

1

High-throughput

0.489

High

648338

USF1
Upstream stimulatory factor 1

1

1

High-throughput

0.489

High

655986

CAH6
Carbonic anhydrase 6

1

3

High-throughput

0.489

High

856596

BAG6
Large proline-rich protein BAG6

1

5

High-throughput

0.489

High

879995

DNSL1
Deoxyribonuclease-1-like 1

1

5

High-throughput

0.489

High

907890

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

6

High-throughput

0.489

High

907891

MFAP4
Microfibril-associated glycoprotein 4

1

3

High-throughput

0.489

High

907892

EP3B
Epididymal secretory protein E3-beta

1

4

High-throughput

0.489

High

907898

FMOD
Fibromodulin

1

2

High-throughput

0.489

High

907905

EP3A
Epididymal secretory protein E3-alpha

1

4

High-throughput

0.489

High

907909

TAZ
Tafazzin

1

3

High-throughput

0.489

High

907911

CL12B
C-type lectin domain family 12 member B

1

16

High-throughput

0.489

High

907912

DB135
Beta-defensin 135

1

2

High-throughput

0.489

High

907913

BRID5
BRICHOS domain-containing protein 5

1

6

High-throughput

0.489

High

907915

LYZL1
Lysozyme-like protein 1

1

4

High-throughput

0.489

High

907917

KI21A
Kinesin-like protein KIF21A

1

3

High-throughput

0.489

High

907918

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

2

High-throughput

0.489

High

907920

CNTRB
Centrobin

1

3

High-throughput

0.489

High

907921

FIBIN
Fin bud initiation factor homolog

1

3

High-throughput

0.489

High

907924

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

6

High-throughput

0.489

High

907927

GGH
Gamma-glutamyl hydrolase

1

5

High-throughput

0.489

High

907930

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

3

High-throughput

0.489

High

907932

SMC6
Structural maintenance of chromosomes protein 6

1

3

High-throughput

0.489

High

907937

CST9L
Cystatin-9-like

1

5

High-throughput

0.489

High

907939

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

1

1

High-throughput

0.489

High

907940

SDF2L
Stromal cell-derived factor 2-like protein 1

1

8

High-throughput

0.489

High

907944

KLC4
Kinesin light chain 4

1

1

High-throughput

0.489

High

907945

CBLN4
Cerebellin-4

1

10

High-throughput

0.489

High

907951

HYOU1
Hypoxia up-regulated protein 1

1

7

High-throughput

0.489

High

188842

TMPS2
Transmembrane protease serine 2

1

14

High-throughput

0.479

High

217983

TGON2
Trans-Golgi network integral membrane protein 2

1

16

High-throughput

0.479

High

774223

BASI
Basigin

1

10

High-throughput

0.479

High

907907

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

17

High-throughput

0.479

High

270235

MTG16
Protein CBFA2T3

1

1

Small-scale

0.470

High

405422

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.464

High

907893

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

3

High-throughput

0.464

High

907901

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

2

High-throughput

0.464

High

907910

SMN
Survival motor neuron protein

1

1

High-throughput

0.464

High

254894

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.445

High

722423

CTR1
High affinity cationic amino acid transporter 1

1

1

High-throughput

0.445

High

877648

SL9A3
Sodium/hydrogen exchanger 3

1

1

High-throughput

0.445

High

907904

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

907950

S39AA
Zinc transporter ZIP10

1

8

High-throughput

0.445

High

907906

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

6

High-throughput

0.437

High

907916

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

170709

CLGN
Calmegin

1

11

High-throughput

0.407

High

505810

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

5

High-throughput

0.407

High

698505

CALX
Calnexin

1

11

High-throughput

0.407

High

907899

DNJC3
DnaJ homolog subfamily C member 3

1

6

High-throughput

0.407

High

907923

PATE1
Prostate and testis expressed protein 1

1

4

High-throughput

0.407

High

907926

S39A7
Zinc transporter SLC39A7

1

8

High-throughput

0.407

High

907942

FBX6
F-box only protein 6

1

16

High-throughput

0.407

High

250514

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.279

Low

347590

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.279

Low

827351

MLH1
DNA mismatch repair protein Mlh1

1

0

High-throughput

0.279

Low

907889

OAZ1
Ornithine decarboxylase antizyme 1

1

0

High-throughput

0.279

Low

907897

HSF2
Heat shock factor protein 2

1

0

High-throughput

0.279

Low

907903

EXOS2
Exosome complex component RRP4

1

0

High-throughput

0.279

Low

907933

SPXN
Spexin

1

0

High-throughput

0.279

Low

907938

ARP5
Actin-related protein 5

1

0

High-throughput

0.279

Low

907946

SPS2L
SPATS2-like protein

1

0

High-throughput

0.279

Low

907947

POLK
DNA polymerase kappa

1

0

High-throughput

0.279

Low

907894

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.265

Low

138025

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.249

Low

907934

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025