HitPredict

Interactor 1: RRP5 (Q05022)
rRNA biogenesis protein RRP5 (Ribosomal RNA-processing protein 5) (U3 small nucleolar RNA-associated protein RRP5) (U3 snoRNA-associated protein RRP5)
Gene: RRP5

Interactor 2: RRP45 (Q05636)
Exosome complex component RRP45 (Ribosomal RNA-processing protein 45)
Gene: RRP45

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	12150911, 37968396, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1729 Sc			1 305
+	Sc
		1050211 RRP5_YEAST (1-1729): 0: 1246: 100.00		RRP42_YEAST (5-247): 1.04e-35: 131: 13.10
+	Sc
		863134 RRP5_YEAST (1-1729): 0: 1246: 100.00		RRP41_YEAST (21-290): 4.41e-25: 102: 13.00
+	Hs
		1130856 RRP5_HUMAN (35-1717): 7.04e-129: 447: 15.89		EXOS4_HUMAN (15-291): 2.69e-46: 158: 11.31
+	Hs
		321622 PRP6_HUMAN (1487-1729): 4.62e-19: 96.3: 15.16		EXOS8_HUMAN (8-285): 1.44e-79: 244: 26.34
+	Hs
		321534 PRP6_HUMAN (1487-1729): 4.62e-19: 96.3: 15.16		EXOS7_HUMAN (5-298): 9.62e-72: 225: 20.60
+	Sa
		1232804 PNP_STAAR (475-680): 7.65e-24: 111: 15.24		PNP_STAAR (9-294): 2.86e-51: 181: 13.47
+	Ec
		421088 PNP_ECOLI (442-682): 4.56e-26: 118: 14.29		PNP_ECOLI (1-294): 4.67e-42: 155: 12.93
+	Mm
		1317241 PNPT1_MOUSE (475-691): 3.95e-13: 76.6: 13.90		PNPT1_MOUSE (9-294): 1.07e-50: 180: 13.71