HitPredict

Interactor 1: PNPT1 (Q8K1R3)
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)
Gene: PNPT1

Interactor 2: PNPT1 (Q8K1R3)
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)
Gene: PNPT1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29222160
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains KH_1~KH_1, KH_1~RNase_PH, KH_1~RNase_PH_C, KH_1~S1, PNPase~PNPase, PNPase~RNase_PH, PNPase~RNase_PH_C, RNase_PH~RNase_PH, RNase_PH~RNase_PH_C, RNase_PH_C~RNase_PH_C, S1~S1
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000957 - mitochondrial RNA catabolic process
GO:0000958 - mitochondrial mRNA catabolic process
GO:0000962 - positive regulation of mitochondrial RNA catabolic process
GO:0000964 - mitochondrial RNA 5'-end processing
and 31 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 783
Mm

1 783
+ Sa
+ Ec
+ At
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ At
+ At
+ At
+ Hs
+ Hs
+ At
+ Dm
+ Dm
+ At
+ Hs
+ Dm
+ Hs

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Last updated: 11Aug2025