Interactor 1: WRN (Q14191)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]
Gene: WRN
Interactor 2: WRIP1 (Q96S55)
ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1)
Gene: WRNIP1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.54 | 0.60 | 0.573 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11301316 |
Identification Methods | two hybrid, affinity chromatography technology, pull down |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0000731 - DNA synthesis involved in DNA repair GO:0003677 - DNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity |
Homologous interactions | 6 |
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Last updated: 15 Jul 2024