HitPredict

Interactor 1: DYN1 (Q05193)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: DNM1

Interactor 2: FNBP1 (Q96RU3)
Formin-binding protein 1 (Formin-binding protein 17) (hFBP17)
Gene: FNBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.690

Property	Details
Experiments	15252009
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005886 - plasma membrane GO:0005905 - clathrin-coated pit GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 617
+	Hs
		896863 DYN2_HUMAN (1-860): 0: 1021: 78.91		FNBP1_HUMAN (1-617): 8.48e-120: 370: 100.00
+	Hs
		896784 DYN2_HUMAN (1-860): 0: 1021: 78.91		FBP1L_HUMAN (1-617): 3.43e-111: 348: 53.80
+	Hs
		896761 DYN2_HUMAN (1-860): 0: 1021: 78.91		CIP4_HUMAN (1-611): 4.98e-96: 308: 49.35
+	Hs
		1050675 DYN1_HUMAN (1-864): 0: 1087: 100.00		MYO1E_HUMAN (86-609): 5.03e-48: 183: 13.58
+	Mm
		810523 DYN1_MOUSE (1-845): 0: 1081: 99.65		PACN1_MOUSE (178-607): 6.54e-37: 145: 11.86
+	Rn
		638965 DYN1_RAT (1-864): 0: 1081: 98.03		PACN1_RAT (178-607): 1.23e-36: 144: 11.86
+	Hs
		896743 DYN2_HUMAN (1-860): 0: 1021: 78.91		MYO1E_HUMAN (86-609): 5.03e-48: 183: 13.58
+	Hs
		896814 DYN2_HUMAN (1-860): 0: 1021: 78.91		FCSD1_HUMAN (7-607): 7.57e-49: 183: 12.42
+	Hs
		1050712 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN1_HUMAN (188-607): 5.1e-23: 104: 12.14
+	Hs
		1050724 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN2_HUMAN (177-607): 4.03e-23: 104: 12.13
+	Hs
		1050684 DYN1_HUMAN (1-864): 0: 1087: 100.00		ITSN1_HUMAN (7-615): 7.84e-15: 80.7: 11.46
+	Mm
		810548 DYN2_MOUSE (1-860): 0: 1022: 79.13		PACN1_MOUSE (178-607): 6.54e-37: 145: 11.86
+	Mm
		810542 DYN1_MOUSE (1-845): 0: 1081: 99.65		ITSN1_MOUSE (7-615): 1.15e-14: 79.9: 10.50
+	Hs
		1050698 DYN1_HUMAN (1-864): 0: 1087: 100.00		NOSTN_HUMAN (403-607): 2.24e-09: 62.2: 17.84
+	Hs
		896877 DYN2_HUMAN (1-860): 0: 1021: 78.91		PACN1_HUMAN (188-607): 5.1e-23: 104: 12.14
+	Hs
		896932 DYN2_HUMAN (1-860): 0: 1021: 78.91		PACN2_HUMAN (177-607): 4.03e-23: 104: 12.13
+	Mm
		810561 DYN2_MOUSE (1-860): 0: 1022: 79.13		PACN2_MOUSE (177-607): 6.26e-22: 101: 11.16
+	Mm
		810562 DYN2_MOUSE (1-860): 0: 1022: 79.13		ITSN1_MOUSE (7-615): 1.15e-14: 79.9: 10.50
+	Hs
		896763 DYN2_HUMAN (1-860): 0: 1021: 78.91		ITSN1_HUMAN (7-615): 7.84e-15: 80.7: 11.46
+	Hs
		220754 DYN2_HUMAN (1-860): 0: 1021: 78.91		PPIP1_HUMAN (286-607): 8.14e-11: 66.6: 13.53