HitPredict

Interactor 1: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Interactor 2: FCSD1 (Q86WN1)
F-BAR and double SH3 domains protein 1 (Protein nervous wreck 2) (NWK2)
Gene: FCHSD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19041431
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0055037 - recycling endosome GO:0061024 - membrane organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 870 Hs			1 690
+	Hs
		1050698 DYN1_HUMAN (1-846): 0: 1002: 79.04		NOSTN_HUMAN (22-536): 4.8e-81: 268: 15.93
+	Hs
		896784 DYN2_HUMAN (1-870): 0: 1057: 100.00		FBP1L_HUMAN (14-613): 1.22e-57: 207: 13.30
+	Hs
		896863 DYN2_HUMAN (1-870): 0: 1057: 100.00		FNBP1_HUMAN (14-614): 1.32e-49: 185: 13.31
+	Hs
		896761 DYN2_HUMAN (1-870): 0: 1057: 100.00		CIP4_HUMAN (13-606): 4.44e-47: 177: 12.99
+	Hs
		1050709 DYN1_HUMAN (1-846): 0: 1002: 79.04		FNBP1_HUMAN (14-614): 1.32e-49: 185: 13.31
+	Hs
		1402036 DYN3_HUMAN (1-870): 0: 994: 78.41		FNBP1_HUMAN (14-614): 1.32e-49: 185: 13.31
+	Hs
		896907 DYN2_HUMAN (1-870): 0: 1057: 100.00		ITSN2_HUMAN (4-628): 1.89e-21: 102: 12.62
+	Hs
		896763 DYN2_HUMAN (1-870): 0: 1057: 100.00		ITSN1_HUMAN (374-631): 8.49e-21: 100: 16.41
+	Mm
		810562 DYN2_MOUSE (1-870): 0: 1057: 98.16		ITSN1_MOUSE (380-631): 4.28e-20: 97.7: 16.41
+	Mm
		810561 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN2_MOUSE (260-608): 3.45e-18: 90.3: 14.62
+	Mm
		810559 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN3_MOUSE (310-605): 7.61e-14: 76.2: 16.83
+	Hs
		896928 DYN2_HUMAN (1-870): 0: 1057: 100.00		PACN3_HUMAN (310-605): 1.15e-13: 75.5: 18.77
+	Dm
		118383 DYN_DROME (6-842): 0: 928: 66.23		M9NE16_DROME (14-606): 2.89e-51: 190: 14.40
+	Hs
		1050684 DYN1_HUMAN (1-846): 0: 1002: 79.04		ITSN1_HUMAN (374-631): 8.49e-21: 100: 16.41
+	Mm
		810542 DYN1_MOUSE (1-844): 0: 1003: 79.23		ITSN1_MOUSE (380-631): 4.28e-20: 97.7: 16.41
+	Rn
		638964 DYN1_RAT (1-846): 0: 994: 78.57		ITSN1_RAT (380-631): 3.31e-20: 98.1: 16.02
+	Dm
		118279 DYN_DROME (6-842): 0: 928: 66.23		M9ND00_DROME (389-615): 2.21e-37: 152: 20.80
+	Hs
		1050723 DYN1_HUMAN (1-846): 0: 1002: 79.04		PACN3_HUMAN (310-605): 1.15e-13: 75.5: 18.77
+	Mm
		237068 DYN1_MOUSE (1-844): 0: 1003: 79.23		NCK2_MOUSE (418-627): 3.73e-13: 73.7: 24.78
+	Hs
		593970 DYN1_HUMAN (1-846): 0: 1002: 79.04		NCK1_HUMAN (477-618): 2.41e-13: 74.1: 26.47