HitPredict

Interactor 1: DYN2 (P39054)
Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM)
Gene: Dnm2

Interactor 2: PACN1 (Q61644)
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)
Gene: Pacsin1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	18456257, 21926968
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048488 - synaptic vesicle endocytosis GO:0048812 - neuron projection morphogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 870 Mm			1 441
+	Hs
		896877 DYN2_HUMAN (1-870): 0: 1090: 98.16		PACN1_HUMAN (1-441): 1.41e-94: 293: 95.05
+	Mm
		810559 DYN2_MOUSE (1-870): 0: 1100: 100.00		PACN3_MOUSE (1-441): 5.49e-85: 268: 49.21
+	Mm
		810561 DYN2_MOUSE (1-870): 0: 1100: 100.00		PACN2_MOUSE (1-441): 1.77e-82: 263: 60.83
+	Hs
		896928 DYN2_HUMAN (1-870): 0: 1090: 98.16		PACN3_HUMAN (1-441): 2.66e-82: 261: 48.98
+	Hs
		896932 DYN2_HUMAN (1-870): 0: 1090: 98.16		PACN2_HUMAN (1-441): 9.66e-80: 256: 59.79
+	Mm
		810523 DYN1_MOUSE (1-868): 0: 1042: 77.74		PACN1_MOUSE (1-441): 1.58e-97: 301: 100.00
+	Hs
		1050712 DYN1_HUMAN (1-847): 0: 1028: 79.18		PACN1_HUMAN (1-441): 1.41e-94: 293: 95.05
+	Hs
		220754 DYN2_HUMAN (1-870): 0: 1090: 98.16		PPIP1_HUMAN (8-441): 9.44e-65: 215: 18.82
+	Hs
		1050723 DYN1_HUMAN (1-847): 0: 1028: 79.18		PACN3_HUMAN (1-441): 2.66e-82: 261: 48.98
+	Hs
		896761 DYN2_HUMAN (1-870): 0: 1090: 98.16		CIP4_HUMAN (15-391): 5.01e-44: 164: 14.66
+	Hs
		896863 DYN2_HUMAN (1-870): 0: 1090: 98.16		FNBP1_HUMAN (11-391): 9.71e-40: 152: 15.54
+	Mm
		810546 DYN2_MOUSE (1-870): 0: 1100: 100.00		SRC8_MOUSE (111-439): 3.34e-36: 141: 16.17
+	Hs
		896936 DYN2_HUMAN (1-870): 0: 1090: 98.16		BAIP2_HUMAN (26-441): 2.95e-34: 136: 14.19
+	Hs
		1050698 DYN1_HUMAN (1-847): 0: 1028: 79.18		NOSTN_HUMAN (22-441): 2.21e-54: 190: 18.22
+	Hs
		1050709 DYN1_HUMAN (1-847): 0: 1028: 79.18		FNBP1_HUMAN (11-391): 9.71e-40: 152: 15.54
+	Mm
		810562 DYN2_MOUSE (1-870): 0: 1100: 100.00		ITSN1_MOUSE (364-439): 3.69e-14: 77.1: 31.58
+	Hs
		896763 DYN2_HUMAN (1-870): 0: 1090: 98.16		ITSN1_HUMAN (365-439): 1.09e-15: 82: 32.00
+	Hs
		896784 DYN2_HUMAN (1-870): 0: 1090: 98.16		FBP1L_HUMAN (241-438): 6.19e-10: 63.2: 14.90
+	Mm
		810542 DYN1_MOUSE (1-868): 0: 1042: 77.74		ITSN1_MOUSE (364-439): 3.69e-14: 77.1: 31.58
+	Hs
		1050684 DYN1_HUMAN (1-847): 0: 1028: 79.18		ITSN1_HUMAN (365-439): 1.09e-15: 82: 32.00