HitPredict

Interactor 1: DSC3 (Q14574)
Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP)
Gene: DSC3

Interactor 2: TMPS4 (Q9NRS4)
Transmembrane protease serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (CAPH2) (Membrane-type serine protease 2) (MT-SP2) [Cleaved into: Transmembrane protease serine 4 catalytic chain]
Gene: TMPRSS4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	34709727
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 437
+	Hs
		177890 DSC3_HUMAN (1-896): 0: 847: 100.00		TMPS2_HUMAN (44-436): 2.07e-111: 338: 34.41
+	Hs
		1055836 DSC3_HUMAN (1-896): 0: 847: 100.00		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80
+	Hs
		1345102 PCDGH_HUMAN (2-464): 7.18e-93: 315: 15.98		TMPS4_HUMAN (1-437): 8.94e-167: 477: 100.00
+	Hs
		580264 CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55		TMPS4_HUMAN (1-437): 8.94e-167: 477: 100.00
+	Hs
		1198237 PCDGH_HUMAN (2-464): 7.18e-93: 315: 15.98		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80
+	Hs
		971071 DSC2_HUMAN (3-350): 7.18e-27: 120: 13.83		TMPS4_HUMAN (1-437): 8.94e-167: 477: 100.00
+	Hs
		177817 CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55		TMPS2_HUMAN (44-436): 2.07e-111: 338: 34.41
+	Hs
		580245 CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80
+	Hs
		971030 DSC2_HUMAN (3-350): 7.18e-27: 120: 13.83		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80