HitPredict

Interactor 1: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Interactor 2: TCPQM (Q96SF2)
T-complex protein 1 subunit theta-like 2 (Chaperonin containing T-complex polypeptide 1 subunit 8-like 2)
Gene: CCT8L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1992 Hs			1 557
+	Sc
		792404 TOM1_YEAST (922-1992): 0: 644: 15.37		TCPH_YEAST (12-547): 0: 541: 20.40
+	Hs
		125246 WWP2_HUMAN (1053-1990): 0: 603: 18.31		TCPG_HUMAN (24-540): 0: 530: 22.89
+	Hs
		125243 WWP2_HUMAN (1053-1990): 0: 603: 18.31		TCPE_HUMAN (24-528): 5.65e-179: 517: 23.79
+	Hs
		1306694 SMUF1_HUMAN (1455-1989): 1.22e-158: 508: 18.46		TCPH_HUMAN (21-534): 0: 545: 20.83
+	Hs
		843061 SMUF1_HUMAN (1455-1989): 1.22e-158: 508: 18.46		TCPQ_HUMAN (1-532): 0: 535: 31.24
+	Hs
		843398 SMUF1_HUMAN (1455-1989): 1.22e-158: 508: 18.46		TCPD_HUMAN (1-521): 1.26e-178: 516: 22.39
+	Hs
		843167 UBE3A_HUMAN (1492-1991): 2.41e-140: 462: 27.02		TCPD_HUMAN (1-521): 1.26e-178: 516: 22.39
+	Sc
		811442 TOM1_YEAST (922-1992): 0: 644: 15.37		TCPQ_YEAST (8-526): 2.4e-53: 192: 27.85
+	Hs
		1306737 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		TCPH_HUMAN (21-534): 0: 545: 20.83
+	Hs
		843092 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		TCPQ_HUMAN (1-532): 0: 535: 31.24
+	Sc
		760677 TOM1_YEAST (922-1992): 0: 644: 15.37		TCPB_YEAST (25-531): 2.52e-35: 140: 25.53
+	Sc
		811399 HUL5_YEAST (1321-1992): 1.29e-147: 483: 20.12		TCPQ_YEAST (8-526): 2.4e-53: 192: 27.85
+	Hs
		1072710 UBE3C_HUMAN (1697-1992): 3.54e-26: 119: 30.57		TCPH_HUMAN (21-534): 0: 545: 20.83
+	Hs
		1192186 HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72		TCPH_HUMAN (21-534): 0: 545: 20.83
+	Hs
		842935 HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72		TCPQ_HUMAN (1-532): 0: 535: 31.24
+	Hs
		826741 HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72		TCPG_HUMAN (24-540): 0: 530: 22.89
+	Hs
		821288 HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72		TCPE_HUMAN (24-528): 5.65e-179: 517: 23.79
+	Hs
		843265 HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72		TCPD_HUMAN (1-521): 1.26e-178: 516: 22.39
+	Sp
		293226 IMA2_SCHPO (371-906): 7.78e-156: 493: 15.12		TCPD_SCHPO (15-524): 4.12e-35: 140: 26.19
+	Sc
		703160 UFD4_YEAST (351-962): 4.64e-35: 149: 17.31		TCPQ_YEAST (8-526): 2.4e-53: 192: 27.85