Protein: LONF1
LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)

Gene: LONF1, LONRF1
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q17RB8

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

168540

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

4

20

High-throughput

0.911

High

1165286

TRI42
Tripartite motif-containing protein 42

3

19

High-throughput

0.871

High

1165265

LONF2
LON peptidase N-terminal domain and RING finger protein 2

2

19

High-throughput

0.811

High

571994

TRI27
Zinc finger protein RFP

2

16

High-throughput

0.783

High

1090671

TRAF2
TNF receptor-associated factor 2

2

18

High-throughput

0.783

High

1165278

ZN774
Zinc finger protein 774

2

4

High-throughput

0.783

High

1165289

CBLL2
E3 ubiquitin-protein ligase CBLL2

2

8

High-throughput

0.783

High

1165292

LNX1
E3 ubiquitin-protein ligase LNX

2

9

High-throughput

0.783

High

1165294

ZFP90
Zinc finger protein 90 homolog

2

2

High-throughput

0.783

High

1165302

ZN653
Zinc finger protein 653

2

11

High-throughput

0.783

High

1165310

ZN426
Zinc finger protein 426

2

4

High-throughput

0.783

High

1165319

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

6

High-throughput

0.783

High

1165320

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

9

High-throughput

0.783

High

1165324

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

19

High-throughput

0.783

High

1165326

IKZF3
Zinc finger protein Aiolos

2

10

High-throughput

0.783

High

1165325

IKZF2
Zinc finger protein Helios

1

10

High-throughput

0.740

High

799167

BRCA1
Breast cancer type 1 susceptibility protein

1

18

High-throughput

0.698

High

1165264

LONF1
LON peptidase N-terminal domain and RING finger protein 1

1

17

High-throughput

0.698

High

1165314

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

18

High-throughput

0.698

High

1022723

XIAP
E3 ubiquitin-protein ligase XIAP

4

5

High-throughput

0.698

High

345889

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

3

13

High-throughput

0.675

High

560865

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

3

3

High-throughput

0.675

High

1118869

BYST
Bystin

3

2

High-throughput

0.675

High

1145955

K1H1
Keratin, type I cuticular Ha1

3

11

High-throughput

0.675

High

1165317

GORS2
Golgi reassembly-stacking protein 2

4

5

High-throughput

0.644

High

1165304

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

2

High-throughput

0.628

High

993599

UBC9
SUMO-conjugating enzyme UBC9

1

20

High-throughput

0.621

High

1165318

PRD16
Histone-lysine N-methyltransferase PRDM16

1

7

High-throughput

0.621

High

1165280

ATL4
ADAMTS-like protein 4

3

2

High-throughput

0.616

High

1165282

KCTD9
BTB/POZ domain-containing protein KCTD9

3

10

High-throughput

0.616

High

1165308

GORS1
Golgi reassembly-stacking protein 1

3

2

High-throughput

0.616

High

210006

CRX
Cone-rod homeobox protein

3

7

High-throughput

0.613

High

341778

K2C75
Keratin, type II cytoskeletal 75

2

6

High-throughput

0.606

High

680890

PSA1
Proteasome subunit alpha type-1

2

6

High-throughput

0.606

High

685208

PAX6
Paired box protein Pax-6

2

6

High-throughput

0.606

High

937472

CDN2D
Cyclin-dependent kinase 4 inhibitor D

2

19

High-throughput

0.606

High

988980

AP2B1
AP-2 complex subunit beta

2

5

High-throughput

0.606

High

1112431

MTMR3
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3

2

10

High-throughput

0.606

High

1165266

LEG9B
Galectin-9B

2

11

High-throughput

0.606

High

1165269

KR133
Keratin-associated protein 13-3

2

1

High-throughput

0.606

High

1165277

TASO2
Protein TASOR 2

2

8

High-throughput

0.606

High

1165279

GASP3
G protein-coupled receptor associated sorting protein 3

2

1

High-throughput

0.606

High

1165285

KRA13
Keratin-associated protein 1-3

2

1

High-throughput

0.606

High

1165297

KRT35
Keratin, type I cuticular Ha5

2

11

High-throughput

0.606

High

1165299

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

2

High-throughput

0.606

High

1165303

RM38
Large ribosomal subunit protein mL38

2

2

High-throughput

0.606

High

1165313

TRIM8
E3 ubiquitin-protein ligase TRIM8

2

18

High-throughput

0.606

High

1165323

ZNHI2
Zinc finger HIT domain-containing protein 2

2

2

High-throughput

0.606

High

1165327

PPR3C
Protein phosphatase 1 regulatory subunit 3C

2

2

High-throughput

0.606

High

1165328

MAGD1
Melanoma-associated antigen D1

2

12

High-throughput

0.606

High

1165316

ISCU
Iron-sulfur cluster assembly enzyme ISCU

2

0

High-throughput

0.602

High

1165281

Q7KZS0
SUMO-conjugating enzyme UBC9

1

20

High-throughput

0.594

High

1165284

KR131
Keratin-associated protein 13-1

2

1

High-throughput

0.584

High

335465

SLU7
Pre-mRNA-splicing factor SLU7

2

0

High-throughput

0.580

High

1165267

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.580

High

1165268

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.580

High

1165270

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.580

High

1165311

KRA33
Keratin-associated protein 3-3

2

0

High-throughput

0.580

High

1165321

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1063287

GOGA2
Golgin subfamily A member 2

2

10

High-throughput

0.574

High

221134

SPY2
Protein sprouty homolog 2

1

2

High-throughput

0.573

High

652526

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

High-throughput

0.573

High

730620

1433S
14-3-3 protein sigma

1

20

High-throughput

0.573

High

1095652

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

15

High-throughput

0.573

High

1165298

KAT5
Histone acetyltransferase KAT5

1

3

High-throughput

0.573

High

1165301

LHX4
LIM/homeobox protein Lhx4

1

4

High-throughput

0.573

High

959476

YPEL3
Protein yippee-like 3

1

1

High-throughput

0.555

High

70224

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

256532

TBX19
T-box transcription factor TBX19

2

1

High-throughput

0.553

High

506728

PRR35
Proline-rich protein 35

2

1

High-throughput

0.553

High

699452

PROP
Properdin

2

4

High-throughput

0.553

High

885254

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.553

High

895723

LHX2
LIM/homeobox protein Lhx2

2

5

High-throughput

0.553

High

1007930

PO6F2
POU domain, class 6, transcription factor 2

2

7

High-throughput

0.553

High

1037719

PAX5
Paired box protein Pax-5

2

6

High-throughput

0.553

High

1056611

PAX8
Paired box protein Pax-8

2

6

High-throughput

0.553

High

1132175

HLX
H2.0-like homeobox protein

2

3

High-throughput

0.553

High

1165272

KCD21
BTB/POZ domain-containing protein KCTD21

2

14

High-throughput

0.553

High

1165291

GABP2
GA-binding protein subunit beta-2

2

16

High-throughput

0.553

High

1165305

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

5

High-throughput

0.553

High

1165309

WDR83
WD repeat domain-containing protein 83

2

9

High-throughput

0.553

High

1165300

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.549

High

415606

HSPB1
Heat shock protein beta-1

1

9

High-throughput

0.541

High

1165296

RSPH1
Radial spoke head 1 homolog

1

4

High-throughput

0.541

High

286660

STX11
Syntaxin-11

1

2

High-throughput

0.523

High

1165283

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.523

High

180529

PLS1
Phospholipid scramblase 1

1

5

High-throughput

0.481

High

583871

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

13

High-throughput

0.481

High

1165290

FXL13
F-box and leucine-rich repeat protein 13

1

4

Small-scale

0.479

High

1165312

KPCD2
Serine/threonine-protein kinase D2

1

16

High-throughput

0.479

High

331014

KI20A
Kinesin-like protein KIF20A

1

15

High-throughput

0.470

High

1165295

Q8WVK1
PLSCR1 protein

1

1

High-throughput

0.470

High

1165322

RIM3A
RIMS-binding protein 3A

1

7

High-throughput

0.470

High

66396

RIM3C
RIMS-binding protein 3C

1

7

High-throughput

0.439

High

288425

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

18

High-throughput

0.439

High

1165273

KHDC1
KH homology domain-containing protein 1

1

1

High-throughput

0.439

High

947003

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

1165275

EFHC2
EF-hand domain-containing family member C2

3

0

High-throughput

0.352

High

1165288

IHO1
Interactor of HORMAD1 protein 1

3

0

High-throughput

0.352

High

873879

KCNJ5
G protein-activated inward rectifier potassium channel 4

2

0

High-throughput

0.328

High

65488

OOEP
Oocyte-expressed protein homolog

2

0

High-throughput

0.316

High

1165274

CD017
Uncharacterized protein C4orf17

2

0

High-throughput

0.316

High

1165276

AVPI1
Arginine vasopressin-induced protein 1

2

0

High-throughput

0.316

High

1165293

MYOZ3
Myozenin-3

2

0

High-throughput

0.316

High

1165306

FACC1
Flagellum-associated coiled-coil domain-containing protein 1

2

0

High-throughput

0.316

High

1165307

VGLL1
Transcription cofactor vestigial-like protein 1

2

0

High-throughput

0.316

High

1165315

KTBL1
KATNB1-like protein 1

2

0

High-throughput

0.316

High

1165287

IQCF2
IQ domain-containing protein F2

1

0

High-throughput

0.299

High

1165271

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025