HitPredict

Interactor 1: APRIO (F7VJQ1)
Alternative prion protein (AltPrP)
Gene: PRNP

Interactor 2: NEK1 (Q96PY6)
Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)
Gene: NEK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36543142
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 73 Hs			1 1258
+	Hs
		104828 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		CTRO_HUMAN (2-1006): 2.28e-143: 481: 16.35
+	Hs
		105876 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		ROCK1_HUMAN (2-1044): 2.54e-143: 471: 15.36
+	Hs
		104936 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		ROCK2_HUMAN (2-1006): 4.42e-141: 465: 17.43
+	Hs
		106929 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		MRCKB_HUMAN (2-924): 5.57e-130: 440: 17.13
+	Hs
		106478 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		MARK4_HUMAN (3-643): 3.94e-137: 438: 16.74
+	Hs
		106162 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		MARK2_HUMAN (3-645): 3.49e-136: 436: 17.20
+	Hs
		104986 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		STK10_HUMAN (2-900): 1.36e-128: 421: 17.29
+	Hs
		105883 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		KCC2D_HUMAN (2-333): 2.31e-119: 381: 25.15
+	Hs
		106649 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		PLK3_HUMAN (4-260): 9.83e-35: 144: 32.05
+	Hs
		105973 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		KS6A2_HUMAN (8-274): 4.4e-19: 95.5: 25.45