HitPredict

Interactor 1: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Interactor 2: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 17353931, 33961781, 28514442, 32707033, 23602568
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, bimolecular fluorescence complementation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 305
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1 655
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024